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HIV disease–related drug reaction is an adverse drug reaction caused by drugs used for the treatment of HIV/AIDS. Image of common antiretroviral drugs to treat HIV infection [ 1 ] Drug reactions are a major cause of mortality and morbidity around the world.
Schematic description of the mechanism of the four classes of available antiretroviral drugs against HIV. There are six classes of drugs, which are usually used in combination, to treat HIV infection. Antiretroviral (ARV) drugs are broadly classified by the phase of the retrovirus life-cycle that the drug inhibits. Typical combinations include ...
Rilpivirine, sold under the brand names Edurant and Rekambys, is a medication, developed by Tibotec, used for the treatment of HIV/AIDS. [5] [6] It is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced side-effect profile compared with older NNRTIs such as efavirenz.
Its FDA approval helped bring down the price of zidovudine (ZDV), the initial anti-HIV drug. [citation needed] Didanosine has weak acid stability and is easily damaged by stomach acid. Therefore, the original formula approved by the FDA used chewable tablets that included an antacid buffering compound to neutralize stomach acid. The chewable ...
Saquinavir, sold under the brand name Invirase among others, is an antiretroviral medication used together with other medications to treat or prevent HIV/AIDS. [4] Typically it is used with ritonavir or lopinavir/ritonavir to increase its effect. [4] It is taken by mouth. [4] Common side effects include nausea, vomiting, diarrhea, and feeling ...
Efavirenz is not effective against HIV-2, as the pocket of the HIV-2 reverse transcriptase has a different structure, which confers intrinsic resistance to the NNRTI class. [ 20 ] As most NNRTIs bind within the same pocket, viral strains which are resistant to efavirenz are usually also resistant to the other NNRTIs, nevirapine and delavirdine .
S omewhere between 60 and 70 million Americans have digestive conditions like inflammatory bowel disease, acid reflux, chronic constipation, irritable bowel syndrome, and hemorrhoids. Some of ...
Dolutegravir is approved for use in a broad population of HIV-infected patients. It can be used to treat HIV-infected adults who have never taken HIV therapy (treatment-naïve) and HIV-infected adults who have previously taken HIV therapy (treatment-experienced), including those who have been treated with other integrase strand transfer inhibitors.