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Late-onset GM2 gangliosidosis may also present as burning dysesthesia. [6] Chemotherapy-induced peripheral neuropathy is a progressive, enduring and often irreversible tingling numbness, intense pain, and hypersensitivity to cold, beginning in the hands and feet and sometimes involving the arms and legs caused by some chemotherapy agents. [7]
Paresthesia is a sensation of the skin that may feel like numbness (technically called hypoesthesia), tingling, pricking, chilling, or burning. [1] It can be temporary or chronic and has many possible underlying causes. [1] Paresthesia is usually painless and can occur anywhere on the body, but most commonly in the arms and legs. [1]
Symptoms typically begin in the feet or hands but can start in other parts of the body. Some people initially experience a more generalized, whole-body pain. The pain is often described as stabbing or burning, or abnormal skin sensations such as tingling or itchiness. In some individuals, the pain is more severe during times of rest or at night.
Most people experience tingling before pain, and a recurring tingling sensation in the hands and feet can help identify diabetes in people who are developing the disease. grafvision/shutterstock 13.
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CIPN involves various symptoms such as tingling, pain, and numbness in the hands and feet. [2] These symptoms can impair activities of daily living, such as typing or dressing, reduce balance, and increase risk of falls and hospitalizations. They can also give cause to reduce or discontinue chemotherapy.
Chemotherapy-induced acral erythema, also known as palmar-plantar erythrodysesthesia or hand-foot syndrome is reddening, swelling, numbness and desquamation (skin sloughing or peeling) on palms of the hands and soles of the feet (and, occasionally, on the knees, elbows, and elsewhere) that can occur after chemotherapy in patients with cancer.
The hands typically get cold when the body or the hand specifically is exposed to cold.” Most of the time cold hands aren’t a cause for concern — they’re simply the result of less blood ...