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Xanthelasma is a sharply demarcated yellowish deposit of cholesterol underneath the skin. [1] It usually occurs on or around the eyelids ( xanthelasma palpebrarum , abbreviated XP). [ 1 ] [ 2 ] While they are neither harmful to the skin nor painful , these minor growths may be disfiguring and can be removed. [ 1 ]
A xanthelasma is a sharply demarcated yellowish collection of cholesterol underneath the skin, usually on or around the eyelids. Strictly, a xanthelasma is a distinct condition, being called a xanthoma only when becoming larger and nodular, assuming tumorous proportions. [3] Still, it is often classified simply as a subtype of xanthoma. [4]
Specifically, Touton giant cells are found in lipid-rich lesions such as those of fat necrosis, xanthoma, xanthelasma and xanthogranulomas. Touton giant cells are also referred to as xanthelasmatic cells due to the fact they are found in lesions associated with xanthomas which are skin growths with yellow, lipid filled deposits.
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High cholesterol levels normally do not cause any symptoms. Yellow deposits of cholesterol-rich fat may be seen in various places on the body such as around the eyelids (known as xanthelasma palpebrarum), the outer margin of the iris (known as arcus senilis corneae), and in the tendons of the hands, elbows, knees, and feet, particularly the Achilles tendon (known as a tendon xanthoma).
Here are links to possibly useful sources of information about Xanthelasma. PubMed provides review articles from the past five years (limit to free review articles ) The TRIP database provides clinical publications about evidence-based medicine .