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A20 cells, also called ATCC TIB-208, is a cell line originally derived from B-cell lymphoma in an old BALB/c mouse. [1] AT20 cells are BALB/c lymphoma cells derived from spontaneous reticulum cell neoplasm. [2] ATCC TIB-208 cells originated from B-cell lymphoma in the reticulum cell sarcoma of an elderly BALB/c mouse. [3]
U-937 cells are a pro-monocytic model cell line used in biomedical research. [1] They were isolated from the histiocytic lymphoma of a 37-year-old male patient in 1974. [2] Due to the relative uniformity of expanded cultures and lower maintenance requirements these cells have been since used as an important tool for studying phagocyte differentiation and different kinds of cell-to-cell ...
TF-1 cells are an immortal cell line derived from the human Erythroleukemia used in biomedical research. [1] This cells are proliferatively responsive to interleukin-3 (IL-3) or granulocyte-macrophage colony-stimulating factor (GM-CSF). [2] TF-1 cells have gene fusion of CBFA2T3-ABHD12. [3]
Although THP-1 cells are of the same lineage, mutations can cause differences as the progeny proliferates. In general, THP-1 cells exhibit a large, round, single-cell morphology. The cells were derived from the peripheral blood of a 1-year-old human male with acute monocytic leukemia. Some of their characteristics are: [1]
K562 cells were the first human immortalised myelogenous leukemia cell line to be established. K562 cells are of the erythroleukemia type, and the cell line is derived from a 53-year-old female chronic myelogenous leukemia patient in blast crisis. [1] [2] The cells are non-adherent and rounded, are positive for the bcr:abl fusion gene, and bear ...
Besides the culture of well-established immortalised cell lines, cells from primary explants of a plethora of organisms can be cultured for a limited period of time before senescence occurs (see Hayflick's limit). Cultured primary cells have been extensively used in research, as is the case of fish keratocytes in cell migration studies. [88 ...
bEnd.3 is a mouse brain cell line derived from BALB/c mice. The cell line is commonly used in vascular research and studies of endothelial brain tissue. [ 1 ] In particular, bEnd.3 cells can serve as blood–brain barrier models for ischemia .
The cell line is commonly used in bone cancer research as a model for testing novel therapies. [2] In 1987 Rodan et al. determined that Saos-2 cells "possess several osteoblastic features and could be useful as a permanent line of human osteoblast-like cells and as a source of bone-related molecules." [3]
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