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"Extraordinary claims require extraordinary evidence" (sometimes shortened to ECREE), [1] also known as the Sagan standard, is an aphorism popularized by science communicator Carl Sagan. He used the phrase in his 1979 book Broca's Brain and the 1980 television program Cosmos .
Such evidence is expected to be empirical evidence and interpretable in accordance with the scientific method. Standards for scientific evidence vary according to the field of inquiry, but the strength of scientific evidence is generally based on the results of statistical analysis and the strength of scientific controls. [citation needed]
In science and history, consilience (also convergence of evidence or concordance of evidence) is the principle that evidence from independent, unrelated sources can "converge" on strong conclusions. That is, when multiple sources of evidence are in agreement, the conclusion can be very strong even when none of the individual sources of evidence ...
Systematic reviews and meta-analyses of randomized controlled trials can provide strong evidence of the clinical efficacy of particular treatments in given scenarios, which may, in turn, be incorporated into medical guidelines or institutional position papers (ideal sources for clinical recommendations). It is normally best to use reviews and ...
The GRADE approach separates recommendations following from an evaluation of the evidence as strong or weak. A recommendation to use, or not use an option (e.g. an intervention), should be based on the trade-offs between desirable consequences of following a recommendation on the one hand, and undesirable consequences on the other.
Concluding that evidence of an extraterrestrial life form (past or present) has been discovered requires proving that a possible biosignature was produced by the activities or remains of life. [1] As with most scientific discoveries, discovery of a biosignature will require evidence building up until no other explanation exists.
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In philosophy of science, strong inference is a model of scientific inquiry that emphasizes the need for alternative hypotheses, rather than a single hypothesis to avoid confirmation bias. The term "strong inference" was coined by John R. Platt , [ 1 ] a biophysicist at the University of Chicago .