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  2. Dehydroepiandrosterone - Wikipedia

    en.wikipedia.org/wiki/Dehydroepiandrosterone

    Dehydroepiandrosterone (DHEA), also known as androstenolone, is an endogenous steroid hormone precursor. [4] It is one of the most abundant circulating steroids in humans. [ 5 ] DHEA is produced in the adrenal glands , [ 6 ] the gonads , and the brain. [ 7 ]

  3. Androgen - Wikipedia

    en.wikipedia.org/wiki/Androgen

    Dehydroepiandrosterone (DHEA) is a steroid hormone produced in the adrenal cortex from cholesterol. [5] It is the primary precursor of both the androgen and estrogen sex hormones. DHEA is also called dehydroisoandrosterone or dehydroandrosterone. Androstenedione (A4) is an androgenic steroid produced by the testes, adrenal cortex, and ovaries.

  4. Androstenedione - Wikipedia

    en.wikipedia.org/wiki/Androstenedione

    Androstenedione is the common precursor of the androgen and estrogen sex hormones. [7] Androstenedione can be biosynthesized in one of two ways. The primary pathway involves conversion of 17α-hydroxypregnenolone to DHEA by way of 17,20-lyase, with subsequent conversion of DHEA to androstenedione via the enzyme 3β-hydroxysteroid dehydrogenase.

  5. Adrenal cortex - Wikipedia

    en.wikipedia.org/wiki/Adrenal_cortex

    15632. Anatomical terminology. [edit on Wikidata] The adrenal cortex is the outer region and also the largest part of the adrenal gland. It is divided into three separate zones: zona glomerulosa, zona fasciculata and zona reticularis. Each zone is responsible for producing specific hormones. It is also a secondary site of androgen synthesis.

  6. Zona reticularis - Wikipedia

    en.wikipedia.org/wiki/Zona_reticularis

    Cells in the zona reticularis produce precursor androgens including dehydroepiandrosterone (DHEA) and androstenedione from cholesterol. [2] DHEA is further converted to DHEA-sulfate via a sulfotransferase, SULT2A1. [3] These precursors are not further converted in the adrenal cortex if the cells lack 17β-Hydroxysteroid dehydrogenase.

  7. Pregnenolone - Wikipedia

    en.wikipedia.org/wiki/Pregnenolone

    Pregnenolone (P5), or pregn-5-en-3β-ol-20-one, is an endogenous steroid and precursor/metabolic intermediate in the biosynthesis of most of the steroid hormones, including the progestogens, androgens, estrogens, glucocorticoids, and mineralocorticoids. [1] In addition, pregnenolone is biologically active in its own right, acting as a ...

  8. Androgen prohormone - Wikipedia

    en.wikipedia.org/wiki/Androgen_prohormone

    Androgen prohormone. An androgen prohormone, or proandrogen, is a prohormone (or prodrug) of an anabolic-androgenic steroid (AAS). They can be prohormones of testosterone or of synthetic AAS, for example, nandrolone (19-nortestosterone). Dehydroepiandrosterone (DHEA), DHEA sulfate (DHEA-S), and androstenedione may all be considered proandrogens ...

  9. Dehydroandrosterone - Wikipedia

    en.wikipedia.org/wiki/Dehydroandrosterone

    Dehydroandrosterone (DHA), or 5-dehydroandrosterone (5-DHA), also known as isoandrostenolone, as well as androst-5-en-3α-ol-17-one, is an endogenous androgen steroid hormone. [1][2] It is the 3α- epimer of dehydroepiandrosterone (DHEA; androst-5-en-3β-ol-17-one) and the 5 (6)- dehydrogenated and non- 5α-reduced analogue of androsterone (5α ...

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