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Kickers, Inc. is a twelve-issue comic book series published by Marvel Comics from 1986 to 1987 as part of the New Universe imprint. Created by Tom DeFalco and Ron Frenz, the series featured a group of former professional American football players for the fictional New York Smashers team who became a group of heroes for hire, calling themselves "Kickers Inc."
Small proteins are a diverse fold class of proteins (usually <100 amino acids long). [ 1 ][ 2 ][ 3 ] Their tertiary structure is usually maintained by disulphide bridges, [ 4 ] metal ligands, [ 5 ] and or cofactors such as heme. Some small proteins serve important regulatory functions by direct interaction with certain enzymes and are therefore ...
Gregory L. Verdine (born June 10, 1959) is an American chemical biologist, biotech entrepreneur, venture capitalist and university professor. [3] He is a founder of the field of chemical biology, [citation needed] which deals with the application of chemical techniques to biological systems. His work has focused on mechanisms of DNA repair and ...
Levinthal's paradox is a thought experiment in the field of computational protein structure prediction; protein folding seeks a stable energy configuration. An algorithmic search through all possible conformations to identify the minimum energy configuration (the native state) would take an immense duration; however in reality protein folding happens very quickly, even in the case of the most ...
A cystine knot is a protein structural motif containing three disulfide bridges (formed from pairs of cysteine residues). The sections of polypeptide that occur between two of them form a loop through which a third disulfide bond passes, forming a rotaxane substructure. The cystine knot motif stabilizes protein structure and is conserved in ...
Glossary. v. t. e. AlphaFold is an artificial intelligence (AI) program developed by DeepMind, a subsidiary of Alphabet, which performs predictions of protein structure. [1] The program is designed as a deep learning system. [2] AlphaFold software has had three major versions. A team of researchers that used AlphaFold 1 (2018) placed first in ...
Cosmological natural selection. Cosmological natural selection, also called the fecund universes, is a hypothesis proposed by Lee Smolin intended as a scientific alternative to the anthropic principle. It addresses why our universe has the particular properties that allow for complexity and life. The hypothesis suggests that a process analogous ...
An alloprotein is a novel synthetic protein containing one or more "non-natural" amino acids.Non-natural in the context means an amino acid either not occurring in nature (novel and synthesised amino acids), [1] or occurring in nature but not naturally occurring within proteins (natural but non-proteinogenic amino acids).