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The 2024 Nobel Prize in chemistry has been awarded to a trio of scientists who used artificial intelligence to “crack the code” of almost all known proteins, the “chemical tools of life.”
Levinthal's paradox is a thought experiment in the field of computational protein structure prediction; protein folding seeks a stable energy configuration. An algorithmic search through all possible conformations to identify the minimum energy configuration (the native state) would take an immense duration; however in reality protein folding happens very quickly, even in the case of the most ...
Small proteins are a diverse fold class of proteins (usually <100 amino acids long). [ 1 ][ 2 ][ 3 ] Their tertiary structure is usually maintained by disulphide bridges, [ 4 ] metal ligands, [ 5 ] and or cofactors such as heme. Some small proteins serve important regulatory functions by direct interaction with certain enzymes and are therefore ...
Kickers, Inc. is a twelve-issue comic book series published by Marvel Comics from 1986 to 1987 as part of the New Universe imprint. Created by Tom DeFalco and Ron Frenz, the series featured a group of former professional American football players for the fictional New York Smashers team who became a group of heroes for hire, calling themselves "Kickers Inc."
ORLANDO, Fla. - Universal's new theme park, "Epic Universe," could open as early as Memorial Day next year, according to a report from The Wall Street Journal. The report suggests that tickets for ...
Gregory L. Verdine (born June 10, 1959) is an American chemical biologist, biotech entrepreneur, venture capitalist and university professor. [3] He is a founder of the field of chemical biology, [citation needed] which deals with the application of chemical techniques to biological systems. His work has focused on mechanisms of DNA repair and ...
The New Universe is an imprint from Marvel Comics that was published in its original incarnation from 1986 to 1989. It was the first line produced by Marvel Comics utilizing a pre-conceived shared universe concept. It was created by Jim Shooter, Archie Goodwin, Eliot R. Brown, John Morelli, Mark Gruenwald, Tom DeFalco, and edited by Michael ...
A cystine knot is a protein structural motif containing three disulfide bridges (formed from pairs of cysteine residues). The sections of polypeptide that occur between two of them form a loop through which a third disulfide bond passes, forming a rotaxane substructure. The cystine knot motif stabilizes protein structure and is conserved in ...