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Atipamezole, sold under the brand name Antisedan among others, is a synthetic α 2 adrenergic receptor antagonist used for the reversal of the sedative and analgesic effects of dexmedetomidine and medetomidine in dogs. Its reversal effect works by competing with the sedative for α 2-adrenergic receptors and displacing them.
Xylazine is a common veterinary drug used for sedation, anesthesia, muscle relaxation, and analgesia in animals such as horses, cattle, and other mammals. [2] In veterinary anesthesia, it is often used in combination with ketamine. Veterinarians also use xylazine as an emetic, especially in cats. [4] Drug interactions vary with different animals.
acepromazine – sedative, tranquilizer, and antiemetic; afoxolaner - antiparasitic; albendazole - anthelminthic; alphaxolone - hypnotic/sedative; alprazolam – benzodiazepine used as an anxiolytic and tranquilizer; altrenogest – used to synchronizes estrus; amantadine – analgesic for chronic pain; aminophylline – bronchodilator; amitraz ...
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It was used in humans during the 1950s as an antipsychotic, [4] but is now almost exclusively used on animals as a sedative and antiemetic. A closely related analogue, chlorpromazine, is still used in humans. The standard pharmaceutical preparation, acepromazine maleate, is used in veterinary medicine in dogs and cats.
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