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Others: frequently increased appetite and weight gain, rarely nausea, rarely high blood pressure. May increase or decrease liver enzyme levels in the blood of some people. [31] The side effects of low-dose doxepin for insomnia in long-term clinical trials (28 to 85 days) in adults and elderly people were as follows: [11]
The incidence of these adverse effects is not totally known as the scarcity of well-designed clinical trials involving doxepin prohibits it. Side effects that are common (based on its pharmacology or the frequency of these side effects with related agents) appear with a * superscript whereas the serious side effects are in bold .
Tricyclic antidepressants, such as desipramine (Norpramin), doxepin, imipramine (Tofranil), nortriptyline (Pamelor) and protriptyline, and tetracyclic antidepressants, such as mirtazapine (Remeron ...
In addition, the study was observational, meaning that it cannot prove cause, like that certain antidepressants cause weight gain or loss. Again, while researchers sought to focus on first-time ...
Many common antidepressants can cause weight gain over time, but that's not a reason to avoid taking medication for mental health issues, experts say. - Joe Raedle/Getty Images/File
Changes in appetite or weight are common among antidepressants but are largely drug-dependent and related to which neurotransmitters they affect. Mirtazapine and paroxetine, for example, may be associated with weight gain and/or increased appetite, [178] [179] [180] while others (such as bupropion and venlafaxine) achieve the opposite effect ...
Doxepin is rarely used to treat depression and anxiety disorders. It can also be used to treat skin conditions like hives, atopic dermatitis and other conditions associated with skin pruritus ...
Dosulepin, also known as dothiepin and sold under the brand name Prothiaden among others, is a tricyclic antidepressant (TCA) which is used in the treatment of depression. [4] [6] [7] Dosulepin was once the most frequently prescribed antidepressant in the United Kingdom, but it is no longer widely used due to its relatively high toxicity in overdose without therapeutic advantages over other TCAs.