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Clobetasol propionate is used for the treatment of various skin disorders including eczema, herpes labialis, [16] psoriasis, and lichen sclerosus.It is also used to treat several auto-immune diseases including alopecia areata, lichen planus (auto immune skin nodules), and mycosis fungoides (T-cell skin lymphoma).
Topical steroids are the most commonly prescribed topical medications for the treatment of rash and ... lichen planus, discoid ... Clobetasol propionate 0.05% ...
Lichen sclerosus (LS) is a chronic, inflammatory skin disease, of unknown cause, which can affect any body part of any person, but has a strong preference for the genitals (penis, vulva), and is also known as balanitis xerotica obliterans when it affects the penis.
PITTSBURGH, Aug. 22, 2024 (GLOBE NEWSWIRE) -- Lipella Pharmaceuticals, Inc. (NASDAQ: LIPO) has launched an Oral Lichen Planus (OLP) Patient Registry. This online platform is designed to enhance research and drive the development of new treatments for OLP, a chronic inflammatory disease affecting the mucous membranes of the mouth.
Clobetasol is a synthetic glucocorticoid corticosteroid. A propionate ester of clobetasol, clobetasol propionate , has also been marketed, and is far more widely used in comparison. [ 2 ] [ 3 ]
Lichen planus may be categorized as affecting mucosal or cutaneous surfaces.. Cutaneous forms are those affecting the skin, scalp, and nails. [10] [11] [12]Mucosal forms are those affecting the lining of the gastrointestinal tract (mouth, pharynx, esophagus, stomach, anus), larynx, and other mucosal surfaces including the genitals, peritoneum, ears, nose, bladder and conjunctiva of the eyes.
Lichen planus Topical formulations are also available for the skin , eyes ( uveitis ), lungs ( asthma ), nose ( rhinitis ), and bowels . Corticosteroids are also used supportively to prevent nausea, often in combination with 5-HT 3 antagonists (e.g., ondansetron ).
Note the propionate groups at the C17α and C21α positions (top right corner). This is a list of corticosteroid esters , including esters of steroidal glucocorticoids and mineralocorticoids . [ 1 ] [ 2 ] [ 3 ]
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