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  2. Sialadenitis - Wikipedia

    en.wikipedia.org/wiki/Sialadenitis

    According to the British Medical Journal (The BMJ) Best Practice on sialadenitis, there are multiple factors to consider during the diagnosis of sialadenitis, including history, presenting signs and symptoms, followed by appropriate investigations in relation to the presenting case. Other factors to also consider include the type of gland ...

  3. Clostridioides difficile infection - Wikipedia

    en.wikipedia.org/wiki/Clostridioides_difficile...

    Signs and symptoms of CDI range from mild diarrhea to severe life-threatening inflammation of the colon. [16]In adults, a clinical prediction rule found the best signs to be significant diarrhea ("new onset of more than three partially formed or watery stools per 24-hour period"), recent antibiotic exposure, abdominal pain, fever (up to 40.5 °C or 105 °F), and a distinctive foul odor to the ...

  4. Clostridioides difficile - Wikipedia

    en.wikipedia.org/wiki/Clostridioides_difficile

    Clostridioides difficile (syn. Clostridium difficile) is a bacterium known for causing serious diarrheal infections, and may also cause colon cancer. [4] [5] It is known also as C. difficile, or C. diff (/ s iː d ɪ f /), and is a Gram-positive species of spore-forming bacteria. [6]

  5. BMJ Best Practice - Wikipedia

    en.wikipedia.org/wiki/BMJ_Best_Practice

    BMJ Best Practice is an online decision-support tool made for clinical decision making support. It was created in 2009 by BMJ. [1] Development

  6. Clostridioides difficile toxin A - Wikipedia

    en.wikipedia.org/wiki/Clostridioides_difficile...

    SEM of Clostridioides difficile bacteria PaLoc Reference: Clostridioides difficile strain 630, DSM 27543, genome GenBank accession number AM180355 Positions 770.154 to 789.973 bp, total locus size 19.8 kb. Clostridioides difficile toxin A (TcdA) is a toxin produced by the bacteria Clostridioides difficile, formerly known as Clostridium ...

  7. Medical guideline - Wikipedia

    en.wikipedia.org/wiki/Medical_guideline

    Plates vi & vii of the Edwin Smith Papyrus (around the 17th century BC), among the earliest medical guidelines. A medical guideline (also called a clinical guideline, standard treatment guideline, or clinical practice guideline) is a document with the aim of guiding decisions and criteria regarding diagnosis, management, and treatment in specific areas of healthcare.

  8. Bezlotoxumab - Wikipedia

    en.wikipedia.org/wiki/Bezlotoxumab

    In June 2016, the Antimicrobial Drugs Advisory Committee of the US Food and Drug Administration [9] voted to recommend approval of Merck's license application for bezlotoxumab by a vote of 10 to 5, generally expressing a willingness to accept that the trials had proven that bezlotoxumab decreased recurrence of C. difficile overall. [10]

  9. Clostridioides difficile toxin B - Wikipedia

    en.wikipedia.org/wiki/Clostridioides_difficile...

    There are different plasmid sizes of C. difficile. The detected molecular weights range from 2.7x10 6 to 100x10 6, but plasmid sizes show no correlation with toxicity. In order to detect the toxin B level in C. difficile, clinicians extensively use cell culture assays derived from stool specimens from patients with PMC.

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