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A zoster vaccine is a vaccine that reduces the incidence of herpes zoster (shingles), a disease caused by reactivation of the varicella zoster virus, which is also responsible for chickenpox. [8] Shingles provokes a painful rash with blisters, and can be followed by chronic pain ( postherpetic neuralgia ), as well as other complications.
Shingles is prevented by immunizing against the causal virus, varicella zoster, using a zoster vaccine. Vaccination is recommended for adults 50 and older. Two versions of the vaccine are available, the live attenuated Zostavax (now discontinued in the US, essentially a larger-dose chickenpox vaccine) and the protein subunit Shingrix. [7]
This is a timeline of the development of prophylactic human vaccines.Early vaccines may be listed by the first year of development or testing, but later entries usually show the year the vaccine finished trials and became available on the market.
Zostavax is a more concentrated formulation of the Varivax vaccine, designed to elicit an immune response in older adults whose immunity to VZV wanes with advancing age. A systematic review by Cochrane (updated in 2023) shows that Zostavax reduces the incidence of shingles by almost 50%.
Drugs or medicines may be withdrawn from commercial markets because of risks to patients, but also because of commercial reasons (e.g. lack of demand and relatively high production costs).
They were introduced in 2000, but discontinued just three years later, according to Mashed. Cinnamon Melts. Essentially a deconstructed cinnamon roll, Cinnamon Melts have also left McDonald's menus.
Ronzoni pastina has been discontinued, but the pasta brand says it "hasn't given up" on bringing the star-shaped pasta back. (Photo: Ronzoni via Instagram/Getty Images)
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