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Maropitant (INN; [3] brand name: Cerenia, used as maropitant citrate , is a neurokinin-1 (NK 1) receptor antagonist developed by Zoetis specifically for the treatment of motion sickness and vomiting in dogs. It was approved by the FDA in 2007, for use in dogs [4] [5] and in 2012, for cats. [6]
Galenic formulation deals with the principles of preparing and compounding medicines in order to optimize their absorption.Galenic formulation is named after Claudius Galen, a 2nd Century AD Greek physician, who codified the preparation of drugs using multiple ingredients.
Hydrogels can be used as drug delivery vehicles, for transdermal application, ophthalmic drug delivery, [11] cancer treatment [12] or for wound dressing. [ 7 ] [ 13 ] As a type of water based formulation, hydrogels are generally less greasy and are easier to be removed than oil-based formulations like organogels. [ 6 ]
Trifluoromethyl group covalently bonded to an R group. The trifluoromethyl group is a functional group that has the formula-CF 3. The naming of is group is derived from the methyl group (which has the formula -CH 3), by replacing each hydrogen atom by a fluorine atom. Some common examples are trifluoromethane H– CF 3, 1,1,1-trifluoroethane H ...
Trifluoracetone is also used in a synthesis of 2-trifluoromethyl-7-azaindoles starting with 2,6-dihalopyridines. The derived chiral imine is used to prepare enantiopure α-trifluoromethyl alanines and diamines by a Strecker reaction followed by either nitrile hydrolysis or reduction.
It is also referred to as perfluoromethanol or trifluoromethyl alcohol. The compound is the simplest perfluoroalcohol . [ 2 ] The substance is a colorless gas, which is unstable at room temperature.
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