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Fig.1) Schematic diagram of the nephron (yellow), relevant circulation (red/blue), and the four methods of altering the filtrate. The nephron is the functional unit of the kidney. [3] This means that each separate nephron is where the main work of the kidney is performed. A nephron is made of two parts:
An estimate of the GFR is used clinically to determine the degree of kidney impairment and to track the progression of the disease. The GFR, however, does not reveal the source of the kidney disease. This is accomplished by urinalysis, measurement of urine protein excretion, kidney imaging, and, if necessary, kidney biopsy. [1]
Diagram outlining movement of ions in nephron, with the collecting ducts on the right. The collecting duct system is the final component of the kidney to influence the body's electrolyte and fluid balance. In humans, the system accounts for 4–5% of the kidney's reabsorption of sodium and 5% of the kidney's reabsorption of water. At times of ...
The renal fascia is a dense, elastic connective tissue envelope enclosing the kidney and adrenal gland, together with the layer of perirenal fat surrounding these two. [1]The renal fascia separates the adipose capsule of kidney from the overlying pararenal fat.
The renal cortex is the outer portion of the kidney between the renal capsule and the renal medulla. [1] In the adult, it forms a continuous smooth outer zone with a number of projections (cortical columns) that extend down between the pyramids.
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The typical mammalian kidney consists of a renal capsule, a peripheral cortex, an internal medulla, one or more renal calyces, and a renal pelvis. [7] Although the calyces or renal pelvis may be absent in some species. [7] The medulla is made up of one or more renal pyramids, [8] forming papillae with their innermost parts. [9]
Diagram of the circulation related to a single glomerulus, associated tubule, and collecting system The renal corpuscle in the cortex (outer layer) of the kidney. At the top, the renal corpuscle containing the glomerulus. The filtered blood exits into the renal tubule as filtrate, at right. At left, blood flows from the afferent arteriole (red ...