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Leukocyte esterase (LE) is an esterase (a type of enzyme) produced by leukocytes (white blood cells). A leukocyte esterase test (LE test) is a urine test for the presence of white blood cells and other abnormalities associated with infection. White blood cells in the urine can indicate a urinary tract infection (UTI). Positive test results may ...
Neutrophil granulocytes are the leukocytes most commonly associated with urinary infections. A positive test for leukocyte esterase normally indicates the presence of bacteria and a positive nitrite test (although it is not always the case). Infections caused by Trichomonas, Chlamydia and yeasts produce leukocyturia without bacteriuria.
The presence of nitrites, which causes a pink color on the reagent strip pad, therefore acts as an indicator of urinary tract infection. [51] The nitrite test is quite specific, meaning that someone is likely to have a UTI if it is positive, but it is not sensitive; a negative result does not reliably indicate that the subject does not have a UTI.
A nitrite test is a standard component of a urinary test strip. A positive test for nitrites in the urine is called nitrituria. This test is commonly used in diagnosing urinary tract infections (UTIs). A positive nitrite test indicates that the cause of the UTI is a Gram-negative organism, most commonly Escherichia coli. The reason for nitrites ...
In complicated or questionable cases, it may be useful to confirm the diagnosis via urinalysis, looking for the presence of urinary nitrites, white blood cells (leukocytes), or leukocyte esterase. [54] Another test, urine microscopy, looks for the presence of red blood cells, white blood cells, or bacteria.
Urinalysis is the most useful test to start the work up in a patient of dysuria. Urinalysis positive for nitrite carries a high predictive value of a positive urine culture. Also, urine dipstick showing leukocytes as equal predictive value as the presence of nitrites. When both are present, the predictive value goes even higher.
False positive COVID-19 tests—when your result is positive, but you aren’t actually infected with the SARS-CoV-2 virus—are a real, if unlikely, possibility, especially if you don’t perform ...
Dogs communicate using olfactory signals in urine. [14] Sometime after leaving the body, urine may acquire a strong "fish-like" odor because of contamination with bacteria that break down urea into ammonia. [citation needed] This odor is not present in fresh urine of healthy individuals; its presence may be a sign of a urinary tract infection.