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Adamantinoma (from Greek adamantinos 'very hard' [1]) is a rare bone cancer, making up less than 1% of all bone cancers. [2] It almost always occurs in the bones of the lower leg [3] and involves both epithelial and osteofibrous tissue. [4] The condition was first described by Fischer in 1913. [5] [6]
Rothmund–Thomson syndrome (i.e. autosomal recessive association of congenital bone defects, hair and skin dysplasias, hypogonadism, and cataracts) is associated with increased risk of this disease. Large doses of Sr-90, nicknamed bone seeker, increases the risk of bone cancer and leukemia in animals and is presumed to do so in people. [10]
A bone tumor is an abnormal growth of tissue in bone, traditionally classified as noncancerous (benign) or cancerous (malignant). [1] [4] Cancerous bone tumors usually originate from a cancer in another part of the body such as from lung, breast, thyroid, kidney and prostate. [1] There may be a lump, pain, or neurological signs from pressure. [1]
When a person has primary bone cancer, the cancer cells are bone cells that have become cancerous. According to the NHS , around 550 cases of primary bone cancer are diagnosed each year in the UK.
Ewing sarcoma occurs about 10- to 20-fold more commonly in people of European descent compared to people of African descent. [49] [10] Ewing sarcoma is the second most common bone cancer in children and adolescents, with poor prognosis and outcome in ~70% of initial diagnoses and 10–15% of relapses. [50]
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Freddie Steinmark (January 27, 1949 – June 6, 1971) was an American college football player for the University of Texas Longhorns.He inspired his teammates by his faith after his diagnosis of bone cancer and subsequent leg amputation during his junior year.
Chondrosarcoma is a bone sarcoma, a primary cancer composed of cells derived from transformed cells that produce cartilage. [1] A chondrosarcoma is a member of a category of tumors of bone and soft tissue known as sarcomas. About 30% of bone sarcomas are chondrosarcomas. [2] It is resistant to chemotherapy and radiotherapy. Unlike other primary ...
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