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Fetal abnormalities are conditions that affect a fetus or embryo, are able to be diagnosed prenatally, and may be fatal or cause disease after birth. They may include aneuploidies, structural abnormalities, or neoplasms. Acardiac twin; Achondrogenesis; Achondroplasia; Adrenal hematoma; Agenesis of the corpus callosum; Amniotic band syndrome ...
The septum pellucidum is a thin, triangular, vertical membrane separating the anterior horns of the left and right lateral ventricles of the brain. It runs as a sheet from the corpus callosum down to the fornix. During fetal development at approximately the twelfth week of gestation, a space forms between two laminae, which is the CSP. At ...
During fetal development, there is a space between the two laminae called the cave of septum pellucidum that, in ninety percent of cases, disappears during infancy. [ 2 ] [ 3 ] The cavum was occasionally referred to as the fifth ventricle , but this is no longer used because the space is usually not continuous with the ventricular system . [ 4 ]
MRI images of three patients in the sagittal plane. A and B: Complete agenesis of the corpus callosum. C: Complete agenesis of both the corpus callosum and the anterior commissure. Laboratory research has demonstrated that individuals with ACC have difficulty transferring more complex information from one hemisphere to the other. [3]
Agenesis of the corpus callosum (ACC) is a rare congenital disorder that is one of the most common brain malformations observed in human beings, [30] in which the corpus callosum is partially or completely absent. ACC is usually diagnosed within the first two years of life, and may manifest as a severe syndrome in infancy or childhood, as a ...
The corpus callosum plays an extremely important role in interhemispheric communication, thus lack of or absence of these neural fibers results in a number of disabilities. [ 12 ] The lemon sign on CT scans of patients refers to the shape of the fetal skull when the frontal bones lose their normal convex contour and appear flattened or inwardly ...
This diagnosis is generally found in routine fetal anomaly scans at 18–22 weeks gestation. It is one of the more common abnormal brain findings on prenatal ultrasound, occurring in around 1–2 per 1,000 pregnancies. [4] In many cases of mild ventriculomegaly, however, there is resolution of ventriculomegaly during the pregnancy.
An image from Popp et al., 2009. [1] The subventricular zone (SVZ) is a region situated on the outside wall of each lateral ventricle of the vertebrate brain. [2] It is present in both the embryonic and adult brain.