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Tooth development begins at week 6 in utero, in the oral epithelium. The process is divided into three stages: Initiation; Morphogenesis and; Histogenesis [2]; At the end of week 7 i.u., localised proliferations of cells in the dental laminae form round and oval swellings known as tooth buds, which will eventually develop into mesenchymal cells and surround the enamel organ.
The tooth bud (sometimes called the tooth germ) is an aggregation of cells that eventually forms a tooth and is organized into three parts: the enamel organ, the dental papilla and the dental follicle. [3] The enamel organ is composed of the outer enamel epithelium, inner enamel epithelium, stellate reticulum and stratum intermedium. [3]
A: enamel organ B: dental papilla C: dental follicle. The dental follicle, also known as dental sac, is made up of mesenchymal cells and fibres surrounding the enamel organ and dental papilla of a developing tooth. [1] It is a vascular fibrous sac [2] containing the developing tooth and its odontogenic organ.
The enamel organ → purely the epithelial component; The tissues which have been derived from each of the three components are: The dental follicle → will develop to become the periodontal ligament, the cementum and the alveolar bone; The dental papilla → will develop to become the dental pulp and the dentine; The enamel organ → will ...
The cervical loop is the location on an enamel organ in a developing tooth where the outer enamel epithelium and the inner enamel epithelium join. The cervical loop is a histologic term indicating a specific epithelial structure at the apical side of the tooth germ, consisting of loosely aggregated stellate reticulum in the center surrounded by ...
In the tooth bud, regions where enamel formation is completed, the enamel organ gives rise to Hertwig's epithelial root sheath, composed of two epithelial layers derived from the external and internal epithelia. The sheath is irregularly fragmented in time and space as it promotes cementum deposition on the newly formed dentin.
The Ca2+ mainly comes from the enamel organ, and not the dental papilla, by either passive, extracellular transportation or active, intracellular transportation. The active route is controlled by ameloblasts so the site of mineralization can have a tightly controlled climate, including modulation of proteins that inhibit mineralization (e.g ...
The Hertwig epithelial root sheath (HERS) or epithelial root sheath is a proliferation of epithelial cells located at the cervical loop of the enamel organ in a developing tooth. Hertwig epithelial root sheath initiates the formation of dentin in the root of a tooth by causing the differentiation of odontoblasts from the dental papilla.