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  2. Bumetanide - Wikipedia

    en.wikipedia.org/wiki/Bumetanide

    Other serious side effects may include hearing loss and low blood platelets. [2] Blood tests are recommended regularly for those on treatment. [2] Safety during pregnancy and breastfeeding is unclear. [3] Bumetanide is a loop diuretic and works by decreasing the reabsorption of sodium by the kidneys. [4] [2]

  3. List of investigational autism and pervasive developmental ...

    en.wikipedia.org/wiki/List_of_investigational...

    Bumetanide oral liquid (S-95008) – sodium–potassium–chloride symporter/cotransporter inhibitor and indirect GABAergic inhibitor [3] [4] Cariprazine (Reagila, Symvenu, Vraylar; MP-214, RGH-188, WID-RGC20) – dopamine D 2 and D 3 receptor partial agonist, serotonin 5-HT 1A receptor partial agonist, serotonin 5-HT 2B receptor antagonist ...

  4. Metolazone - Wikipedia

    en.wikipedia.org/wiki/Metolazone

    Serious, though rare, side effects include aplastic anemia, pancreatitis, agranulocytosis, and angioedema. Metolazone, like other thiazide diuretics, may unmask latent diabetes mellitus or exacerbate gout, especially by interacting with medicines used to treat gout.

  5. Memantine - Wikipedia

    en.wikipedia.org/wiki/Memantine

    [8] [9] Memantine exposure is linear over a dose range of 10 to 40 mg. [8] Peak levels after a single 20 mg dose were found to be 24 to 29 μg/L (0.13–0.16 μmol/L or μM). [8] Steady-state levels of memantine with 20 mg/day are in the range of 0.5 to 1.0 μM.

  6. Beers criteria - Wikipedia

    en.wikipedia.org/wiki/Beers_Criteria

    The Beers Criteria for Potentially Inappropriate Medication Use in Older Adults, commonly called the Beers List, [1] are guidelines published by the American Geriatrics Society (AGS) for healthcare professionals to help improve the safety of prescribing medications for adults 65 years and older in all except palliative settings.

  7. Amiloride - Wikipedia

    en.wikipedia.org/wiki/Amiloride

    The drug was discovered as part of a screening process of chemicals that reversed the effects of mineralocorticoids in vivo. [27] Amiloride was the only drug in the screen that was capable of causing the excretion of sodium (natriuresis) without a concomitant urinary excretion of potassium (kaliuresis). [27]

  8. Indapamide - Wikipedia

    en.wikipedia.org/wiki/Indapamide

    Two systematic reviews identified that indapamide with or without perindopril significantly reduced all cause mortality in young-elderly patients with a history of stroke, cardiovascular disease and type 2 diabetes mellitus, when greater reductions in mean office blood pressure are achieved, significant cardiovascular benefit was only observed ...

  9. Hydrochlorothiazide - Wikipedia

    en.wikipedia.org/wiki/Hydrochlorothiazide

    Hydrochlorothiazide, sold under the brand name Hydrodiuril among others, is a diuretic medication used to treat hypertension and swelling due to fluid build-up. [4] Other uses include treating diabetes insipidus and renal tubular acidosis and to decrease the risk of kidney stones in those with a high calcium level in the urine. [4]

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