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One of the principal causes of arterial stiffening with age is vascular calcification. Vascular calcification is the deposition of mineral in the form of calcium phosphate salts in the smooth muscle-rich medial layer of large arteries including the aorta. DNA damage, especially oxidative DNA damage, causes accelerated vascular calcification. [11]
The cause is unknown, but it may be due to an abnormal immune response. [2] Risk factors include family history, certain genetic factors, and exposure to silica . [ 3 ] [ 4 ] [ 5 ] The underlying mechanism involves the abnormal growth of connective tissue , which is believed to be the result of the immune system attacking healthy tissues. [ 6 ]
Ectopic calcification is a pathologic deposition of calcium salts in tissues or bone growth in soft tissues.This can be a symptom of hyperphosphatemia.Formation of osseous tissue in soft tissues such as the lungs, eyes, arteries, or other organs is known as ectopic calcification, dystrophic calcification, or ectopic ossification.
Causes and treatments for white spots on nails Trauma "The most common cause of a white spot is trauma," Lipner says. And, when trauma is the culprit, it's often from manicuring.Filing, gel ...
2. You buffed your nails too much. Just as moisture-laden nails can be prone to peeling and splitting, so can nails that are dried out from too much buffing, according to Dr. Peters.
Calcinosis is the formation of calcium deposits in any soft tissue. [1] It is a rare condition that has many different causes. These range from infection and injury to systemic diseases like kidney failure .
Plus, because nails need a variety of vitamins to grow, nutritional deficiencies in biotin, zinc, vitamin D, and protein can also cause peeling nails, adds Dr. Kamangar. 2. You get regular manicures.
Although overall well-being is not typically determined by nail health, fissures, nail fissures (or breaks) and calcium spots are minor indications of inner health. [2] Hapalonychia is known to occur in persons with myxedema , rheumatoid arthritis , anorexia , bulimia , Hansen's disease , Raynaud phenomenon , oral retinoid therapy , and ...