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Noradrenergic and specific serotonergic antidepressants (NaSSAs) are a class of psychiatric drugs used primarily as antidepressants. [1] They act by antagonizing the α 2 -adrenergic receptor and certain serotonin receptors such as 5-HT 2A and 5-HT 2C , [ 1 ] but also 5-HT 3 , [ 1 ] 5-HT 6 , and/or 5-HT 7 in some cases.
Alpha wave biofeedback has gained interest for having some successes in humans for seizure suppression and for treatment of depression. [35] Alpha waves again gained interest in regards to an engineering approach to the science fiction challenge of psychokinesis, i.e. control of movement of a physical object using energy emanating from a human ...
However, the serotonin receptor antagonism has side effects such as weight gain and impaired movement. [11] Hence, alpha-2 blockers are not used clinically due to its extensive binding. Similar to the alpha-1 blocker, the alpha-2 family will also present the first-dose effect , but it is generally less pronounced compared with the alpha-1 blockers.
So Lexapro 20 mg side effects are the same as the side effects of 10 mg of Lexapro, but the 20 mg dose may have increased effects. But there’s no need for alarm.
Researchers have developed a tool that allows people to rate their concern about common side effects of antidepressants. The tool ranks potential treatment options in a visual display that highlights the drugs with side effects of least concern to an individual. [134] [135]
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Prolonged QT interval (less common than with most other atypical antipsychotic drugs) [6] Speech disorder; Electrolyte abnormalities including hyponatraemia, hypokalaemia, hypocalcaemia, etc. Hypertension; Dysphagia; Oropharyngeal spasm; Laryngospasm; Hepatitis; Jaundice; Hypersalivation; Chest pain; Urinary retention or incontinence; Alopecia ...
There is one study supporting the use of a novel combination of dextromethorphan and low dose quinidine in alleviating symptoms of easy laughing and crying (pseudobulbar affect); these are a type of rather severe uncontrollable behaviors which can be present in various neurological pathologies such as amyotrophic lateral sclerosis and multiple ...
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