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In physiology, a stimulus [1] is a change in a living thing's internal or external environment. This change can be detected by an organism or organ using sensitivity, and leads to a physiological reaction. [ 2 ]
The stimulation of a mechanoreceptor causes mechanically sensitive ion channels to open and produce a transduction current that changes the membrane potential of the cell. [10] Typically the mechanical stimulus gets filtered in the conveying medium before reaching the site of mechanotransduction. [ 11 ]
The principle of progressive overload suggests that the continual increase in the total workload during training sessions will stimulate muscle growth and strength gain by muscle hypertrophy. [2] This improvement in overall performance will, in turn, allow an athlete to keep increasing the intensity of their training sessions.
The best approach to specifically achieve muscle growth remains controversial (as opposed to focusing on gaining strength, power, or endurance); it was generally considered that consistent anaerobic strength training will produce hypertrophy over the long term, in addition to its effects on muscular strength and endurance.
The muscle fibers belonging to one motor unit can be spread throughout part, or most of the entire muscle, depending on the number of fibers and size of the muscle. [2] [3] When a motor neuron is activated, all of the muscle fibers innervated by the motor neuron are stimulated and contract. The activation of one motor neuron will result in a ...
Stretch-activated ion channels are required for the initial formation of an action potential from a mechanical stimulus, for example by the mechanoreceptors in vibrissae (whiskers) of some animals such as rodents. Afferent nerve fibers responsible for sensory stimulus detection and feedback are especially sensitive to stimulation.
The gastrocnemius muscle is heterogeneous, composed of both "red" and "pale" muscle, and thus containing fast-twitch high force fibers. Henneman's and colleagues took advantage of the differences between the soleus and gastrocnemius muscles to show that the neurons innervating the soleus muscle:
For asynchronous muscles, neural inputs are typically thought of as an "on-off" switch while mechanical stimulus leads to individual muscle contractions. However, recent studies using genetically engineered Drosophila revealed correlations between [Ca 2+] and force production. [5] Further work has shown bilateral calcium asymmetries in ...