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Fatigue in a medical context is used to cover experiences of low energy that are not caused by normal life. [2] [3]A 2021 review proposed a definition for fatigue as a starting point for discussion: "A multi-dimensional phenomenon in which the biophysiological, cognitive, motivational and emotional state of the body is affected resulting in significant impairment of the individual's ability to ...
Post-exertional malaise (PEM), sometimes referred to as post-exertional symptom exacerbation (PESE) [1] or post-exertional neuroimmune exhaustion (PENE), [2] is a worsening of symptoms that occurs after minimal exertion. It is the hallmark symptom of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and common in long COVID and ...
Exhaustion disorder or stress-induced exhaustion disorder (ED, Swedish: utmattningssyndrom) is a diagnosis used in Swedish healthcare to indicate a maladaptive stress disorder more severe than adjustment disorder. Common signs include exhaustion, reduced cognitive ability and a range of physical symptoms. The symptoms develop gradually as a ...
Central nervous system fatigue, or central fatigue, is a form of fatigue that is associated with changes in the synaptic concentration of neurotransmitters within the central nervous system (CNS; including the brain and spinal cord) which affects exercise performance and muscle function and cannot be explained by peripheral factors that affect muscle function.
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Heat exhaustion is a heat-related illness characterized by the body's inability to effectively cool itself, typically occurring in high ambient temperatures or during intense physical exertion. In heat exhaustion, core body temperature ranges from 37 °C to 40 °C (98.6 °F to 104 °F).
She has developed the concept of an 'exhaustion funnel', to illustrate the way in which preoccupations can be narrowed by over-concentration on work. [ 3 ] She was the 2022 recipient of the ECNP Neuropsychopharmacology (ENA) Award, which recognises exceptional research achievements in applied and translational neuroscience.