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Post-exertional malaise (PEM), sometimes referred to as post-exertional symptom exacerbation (PESE) [1] or post-exertional neuroimmune exhaustion (PENE), [2] is a worsening of symptoms that occurs after minimal exertion. It is the hallmark symptom of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and common in long COVID and ...
Central nervous system fatigue, or central fatigue, is a form of fatigue that is associated with changes in the synaptic concentration of neurotransmitters within the central nervous system (CNS; including the brain and spinal cord) which affects exercise performance and muscle function and cannot be explained by peripheral factors that affect muscle function.
They, however, also wrote that burnout can mean "everything from fatigue to a major depression and now seems to have become an alternative word for depression but with less serious significance" (p. 434). In 2005, the Swedish Board of Health and Welfare adopted a category described as "exhaustion disorder." [51] Treatment programs followed.
Exhaustion disorder or stress-induced exhaustion disorder (ED, Swedish: utmattningssyndrom) is a diagnosis used in Swedish healthcare to indicate a maladaptive stress disorder more severe than adjustment disorder. Common signs include exhaustion, reduced cognitive ability and a range of physical symptoms. The symptoms develop gradually as a ...
Fatigue in a medical context is used to cover experiences of low energy that are not caused by normal life. [2] [3]A 2021 review proposed a definition for fatigue as a starting point for discussion: "A multi-dimensional phenomenon in which the biophysiological, cognitive, motivational and emotional state of the body is affected resulting in significant impairment of the individual's ability to ...
Emotional exhaustion is a symptom of burnout, [1] a chronic state of physical and emotional depletion that results from excessive work or personal demands, or continuous stress. [2] It describes a feeling of being emotionally overextended and exhausted by one's work.
Severe fatigue may come on suddenly and make it difficult to be active at all. [33] The impact of fatigue can be severe and pose more of a problem than the pain. [35] Fatigue is a complicated, multifactorial, and vexing symptom that is highly prevalent (76%) and stubbornly persistent, as evidenced by longitudinal studies over 5 years. [36]
Fatigue can be both physical and mental. Physical fatigue is the inability to continue functioning at the level of one's normal abilities; a person with physical fatigue cannot lift as heavy a box or walk as far as he could if not fatigued. [3] [4] [5] Mental fatigue, on the other hand, rather manifests in sleepiness or slowness. A person with ...
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