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Aztreonam, sold under the brand name Azactam among others, is an antibiotic used primarily to treat infections caused by gram-negative bacteria such as Pseudomonas aeruginosa. [ 2 ] [ 3 ] This may include bone infections , endometritis , intra abdominal infections , pneumonia , urinary tract infections , and sepsis . [ 2 ]
Narrow-spectrum antibiotics have low propensity to induce bacterial resistance and are less likely to disrupt the microbiome (normal microflora). [3] On the other hand, indiscriminate use of broad-spectrum antibiotics may not only induce the development of bacterial resistance and promote the emergency of multidrug-resistant organisms, but also cause off-target effects due to dysbiosis.
Aztreonam/avibactam, sold under the brand name Emblaveo, is a fixed-dose combination antibacterial medication used for the treatment of aerobic Gram-negative infections. [4] It is a combination of aztreonam , a monobactam antibacterial; and avibactam , a beta-lactamase inhibitor . [ 4 ]
What new breed joins the 2024 National Dog Show? In 2023, there were 199 breeds represented at the Thanksgiving Day Dog Show. In 2024, a new breed will make its debut alongside 204 others.
Bactericidal for both Gram-positive and Gram-negative organisms and therefore useful for empiric broad-spectrum antibacterial coverage. (Notes: MRSA resistance to this class. All are active against Pseudomonas aeruginosa except ertapenem.) Gastrointestinal upset and diarrhea; Nausea; Seizures; Headache; Rash and allergic reactions
Aztreonam is the archetypal monobactam. [6] Other monobactams include tigemonam , [ 7 ] nocardicin A , carumonam and tabtoxin . An example of a monobactam that lacks antibiotic activity, but is used clinically for other purposes, is the cholesterol absorption inhibitor ezetimibe which is used to treat hypercholesterolemia .
The Central Asian Shepherd Dog, also known as the Alabay, Alabai (Turkmen: Alabaý, Kazakh: Төбет) and Turkmen Wolf-Hound (Туркменский волкодав), [2] is a livestock guardian dog breed. Traditionally, the breed was used for guarding sheep and goat herds, as well as to protect and for guard duty.
The β-lactam core structures. (A) A penam.(B) A carbapenam.(C) An oxapenam.(D) A penem.(E) A carbapenem.(F) A monobactam.(G) A cephem.(H) A carbacephem.(I) An oxacephem. This is a list of common β-lactam antibiotics—both administered drugs and those not in clinical use—organized by structural class.
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