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Mirvetuximab soravtansine, sold under the brand name Elahere, is a medication used as a treatment for epithelial ovarian cancer, fallopian tube cancer, or primary peritoneal cancer. [ 2 ] [ 5 ] Mirvetuximab soravtansine is a folate receptor alpha directed antibody and microtubule inhibitor conjugate.
The mirvetuximab, which has been submitted for FDA approval, is being developed as a monotherapy or a standalone treatment for ovarian cancer. [7] [8] Other products currently in clinical-stage development include: [9] IMGN853, (mirvetuximab soravtansine) targeting FRα, and using DM4. [10] IMGN529, targeting CD37 for Non-Hodgkin lymphoma (NHL ...
Therapeutic, diagnostic and preventive monoclonal antibodies are clones of a single parent cell. When used as drugs, the International Nonproprietary Names (INNs) end in -mab.
Cantuzumab ravtansine (huC242-SPDB-DM4) is an antibody-drug conjugate designed for the treatment of cancers. The humanized monoclonal antibody cantuzumab (huC242) is linked to a cytotoxic agent, ravtansine (DM4). [1] It uses a more hindered disulfide linkage than cantuzumab mertansine. [2]
Polatuzumab vedotin, sold under the brand name Polivy, is a CD79b-directed antibody-drug conjugate medication used for the treatment of diffuse large B-cell lymphoma . [6] It was developed by the Genentech subsidiary of Roche .
Jacob Kepler/Bloomberg via Getty ImagesCaesars Palace casino in Las Vegas. Plenty of stocks go up and down in any given week. The gainers inspire us to keep investing. The decliners keep greed in ...
For the first time in two decades, the Food and Drug Administration (FDA) has approved a new class of medication that provides an alternative to addictive opioids for patients looking to manage ...
The new drug is intended for treatment of moderate to severe acute pain in adults. Common Pain Reliever Could Cause Medical Complications In Some People Over 65, Study Suggests.