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Specifically, it is an aggressive malignant neoplasm that arises from primitive transformed cells of mesenchymal origin (and thus a sarcoma) and that exhibits osteoblastic differentiation and produces malignant osteoid. [ 1] Osteosarcoma is the most common histological form of primary bone sarcoma. [ 2] It is most prevalent in teenagers and ...
Osteonecrosis of the jaw ( ONJ) is a severe bone disease ( osteonecrosis) that affects the jaws (the maxilla and the mandible ). Various forms of ONJ have been described since 1861, and a number of causes have been suggested in the literature. Osteonecrosis of the jaw associated with bisphosphonate therapy, which is required by some cancer ...
Trismus is a condition of restricted opening of the mouth. [ 1][ 2] The term was initially used in the setting of tetanus. [ 2] Trismus may be caused by spasm of the muscles of mastication or a variety of other causes. [ 3] Temporary trismus occurs much more frequently than permanent trismus. [ 4] It is known to interfere with eating, speaking ...
H&E stain. Multiple endocrine neoplasia type 2B (MEN 2B) is a genetic disease that causes multiple tumors on the mouth, eyes, and endocrine glands. It is the most severe type of multiple endocrine neoplasia, [ 2] differentiated by the presence of benign oral and submucosal tumors in addition to endocrine malignancies.
Burning mouth syndrome ( BMS) is a burning, tingling or scalding sensation in the mouth, lasting for at least four to six months, with no underlying known dental or medical cause. [ 3][ 7] No related signs of disease are found in the mouth. [ 3] People with burning mouth syndrome may also have a subjective xerostomia (dry mouth sensation where ...
White dog shaker syndrome causes full body tremors in small, white dog breeds. It is most common in West Highland White Terriers, Maltese, Bichons, and Poodles. [6] Wobbler disease (cervical instability) is a condition of the cervical vertebrae that causes an unsteady gait and weakness in dogs.
In dogs, hip dysplasia is an abnormal formation of the hip socket that, in its more severe form, can eventually cause lameness and arthritis of the joints. It is a genetic (polygenic) trait that is affected by environmental factors. It is common in many dog breeds, particularly the larger breeds, and is the most common single cause of arthritis ...
Gorham's disease (pronounced GOR-amz), also known as Gorham vanishing bone disease and phantom bone disease, [1] is a very rare skeletal condition of unknown cause.It is characterized by the uncontrolled proliferation of distended, thin-walled vascular or lymphatic channels within bone, which leads to resorption and replacement of bone with angiomas and/or fibrosis.