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Serpiginous choroiditis, also known as geographic helicoid peripapillary choroidopathy (GHPC), is a rare, chronic, progressive, and recurrent bilateral inflammatory disease involving the retinal pigment epithelium (RPE), the choriocapillaries, and the choroid. [1] It affects adult men and women equally in the second to seventh decades of life. [2]
In contrast, white dots appear later in the disease stages of birdshot choroidopathy, serpiginous choroiditis, and acute posterior multifocal placoid pigment epitheliopathy. The white dots in these diseases may be present throughout the entire fundus, larger (50 to 500 μm), and tend to clump together.
Serpiginous, first known to be used in the 15th century, is a term from Latin serpere (“to creep”), usually referring to a creeping, snakelike or slowly progressive skin disease. [ 1 ] [ 2 ]
Chorioretinitis is an inflammation of the choroid (thin pigmented vascular coat of the eye) and retina of the eye. It is a form of posterior uveitis.Inflammation of these layers can lead to vision-threatening complications.
[4] [5] According to typical descriptions, angioma serpiginosum has an erythematous backdrop with a purple to coppery-red punctate look that clusters together in serpiginous or gyrate patterns. [ 3 ] It is often observed that the illness progresses gradually, starting as little asymptomatic lesions that expand and coalesce with central clearing ...
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The etiology of multiple evanescent white dot syndrome is currently unknown but two potential origins have been postulated. Gass, et. al. suggests a virus invades retinal photoreceptors through cell-to-cell transmission via either the ora serrata or optic disc margin. [3]
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