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The mitotic index is a measure of cellular proliferation. [1] It is defined as the percentage of cells undergoing mitosis in a given population of cells. Mitosis is the division of somatic cells into two daughter cells. Durations of the cell cycle and mitosis vary in different cell types. An elevated mitotic index indicates more cells are dividing.
The most commonly used methods in evaluating a proliferative index include mitotic indexing, thymidine-labeling index, bromodeoxyuridine assay, the determination of fraction of cells in various phases of cell cycle, and the immunohistochemical evaluation of cell cycle-associated proteins.
This is an accepted version of this page This is the latest accepted revision, reviewed on 29 January 2025. Process in which chromosomes are replicated and separated into two new identical nuclei For the type of cell division in sexually reproducing organisms used to produce gametes, see Meiosis. For excessive constriction of the pupils, see Miosis. For the parasitic infestation, see Myiasis ...
Anaphase is a very short stage of the cell cycle and it occurs after the chromosomes align at the mitotic plate. Kinetochores emit anaphase-inhibition signals until their attachment to the mitotic spindle. Once the final chromosome is properly aligned and attached the final signal dissipates and triggers the abrupt shift to anaphase. [26]
Altitudinal zones of Andes Mountains and corresponding communities of agriculture and livestock raised. Human populations have developed agricultural production strategies to exploit varying characteristics of altitudinal zones. Elevation, climate, and soil fertility set upper limits on types of crops that can reside in each zone.
The climate and ecology of different locations on the globe naturally separate into life zones, depending on elevation, latitude, and location.The generally strong dependency on elevation is known as altitudinal zonation: the average temperature of a location decreases as the elevation increases.
This diagram depicts the organization of a typical mitotic spindle found in animal cells. Chromosomes are attached to kinetochore microtubules via a multiprotein complex called the kinetochore . Polar microtubules interdigitate at the spindle midzone and push the spindle poles apart via motor proteins.
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