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  2. Anti-amyloid drugs - Wikipedia

    en.wikipedia.org/wiki/Anti-amyloid_drugs

    Anti-amyloid drugs, also known as anti-amyloid antibodies (AAA), [1] are a class of monoclonal antibodies developed to treat Alzheimer's disease. The first drug in the class to be developed, in the early 2000s, is bapineuzumab , but it did not show effectiveness in later-stage trials. [ 2 ]

  3. New test may tell who is prone to side effects from Alzheimer ...

    www.aol.com/test-may-tell-prone-side-153000197.html

    Since July 2023, three anti-amyloid medications have been FDA-approved for the treatment of Alzheimer’s disease with more in development. A potential and serious side effect of anti-amyloid ...

  4. Alzheimer's: Are newly approved drugs making a real-life ...

    www.aol.com/alzheimers-newly-approved-drugs...

    The anti-amyloid antibodies donanemab, aducanumab, and lecanemab are the only therapies targeting beta-amyloid aggregates to gain FDA approval. ... it has been argued that currently available ...

  5. New drug's potentially fatal side effects obscured by ... - AOL

    www.aol.com/news/drugs-potentially-fatal-side...

    The FDA had proposed that companies testing new anti-amyloid drugs exclude any volunteer from clinical trials who had more than two brain microbleeds, according to an Alzheimer's Assn. report.

  6. Aducanumab - Wikipedia

    en.wikipedia.org/wiki/Aducanumab

    Aducanumab, sold under the brand name Aduhelm, is a monoclonal antibody designed to treat Alzheimer's disease. [2] [3] It is a monoclonal antibody [3] [2] that targets aggregated forms (plaque) [4] [5] of amyloid beta (Aβ) found in the brains of people with Alzheimer's disease to reduce its buildup.

  7. Donanemab - Wikipedia

    en.wikipedia.org/wiki/Donanemab

    The US Food and Drug Administration (FDA) label for donanemab contains a boxed warning about amyloid-related imaging abnormalities. [1]Side effects may include infusion-related reactions, with symptoms such as flu-like symptoms, nausea, vomiting and changes in blood pressure, and hypersensitivity reactions, including anaphylaxis (severe, life-threatening allergic reaction) and angioedema ...

  8. ‘Major breakthrough’ as dementia drug found to ‘slow ...

    www.aol.com/major-breakthrough-dementia-drug...

    “The results are consistent in size with those found in earlier phase trials with other anti-amyloid drugs, and with the positive, controversial trial in aducanumab. This convergence strengthens ...

  9. Solanezumab - Wikipedia

    en.wikipedia.org/wiki/Solanezumab

    The Anti-Amyloid Treatment in Asymptomatic Alzheimer’s (A4) study is a phase 3 clinical trial to evaluate whether solanezumab can slow cognitive decline in cognitively unimpaired older adults with elevated levels of amyloid β.

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