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Estrogen, progesterone, and human chorionic gonadotropin (hCG) levels throughout pregnancy. Estrogen, progesterone, and 17α-hydroxyprogesterone (17α-OHP) levels during pregnancy in women. [ 1 ] The dashed vertical lines separate the trimesters .
Progesterone is used as part of hormone replacement therapy in people who have low progesterone levels, and for other reasons. For purposes of comparison with normal physiological circumstances, luteal phase levels of progesterone are 4 to 30 ng/mL, while follicular phase levels of progesterone are 0.02 to 0.9 ng/mL, menopausal levels are 0.03 to 0.3 ng/mL, and levels of progesterone in men ...
The levels of hCG in the body increase rapidly in the first few weeks of pregnancy, doubling every 48–72 hours. [7] The highest level of hCG is reached in week 10 or week 11, later the levels of hCG can be used to estimate the age of the fetus and monitor the progress of the pregnancy. [6]
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The net effect is an increase of free cortisol. This contributes to insulin resistance of pregnancy and possibly striae. [5] Despite the increase in cortisol, the pregnant mom does not exhibit Cushing syndrome or symptoms of high cortisol. One theory is that high progesterone levels act as an antagonist to the cortisol. The adrenal gland also ...
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Levels of estrogen and progesterone in normal human pregnancy are very high. [6] Estradiol levels are 1,000 to 5,000 pg/mL during the first trimester, 5,000 to 15,000 pg/mL during the second trimester, and 10,000 to 40,000 pg/mL during the third trimester, [ 38 ] with a mean of 25,000 pg/mL at term and levels as high as 75,000 pg/mL measurable ...
Levels of progesterone during pregnancy are up to 100-fold higher than during normal menstrual cycling, although levels increase gradually over the course of pregnancy. [135] Oral dosages of progesterone of as high as 3,600 mg/day have been assessed in clinical trials, with the main side effect being sedation. [ 136 ]