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Thyroid hormone uptake (T uptake or T 3 uptake) is a measure of the unbound thyroxine binding globulins in the blood, that is, the TBG that is unsaturated with thyroid hormone. [2] Unsaturated TBG increases with decreased levels of thyroid hormones. It is not directly related to triiodothyronine, despite the name T 3 uptake. [2] Reference ranges:
Acid–base and blood gases are among the few blood constituents that exhibit substantial difference between arterial and venous values. [6] Still, pH, bicarbonate and base excess show a high level of inter-method reliability between arterial and venous tests, so arterial and venous values are roughly equivalent for these. [44]
Despite its low concentration, TBG carries the majority of T 4 in the blood plasma. Due to the very low concentration of T 4 and T 3 in the blood, TBG is rarely more than 25% saturated with its ligand. Unlike transthyretin and albumin, TBG has a single binding site for T 4 /T 3. TBG is synthesized primarily in the liver as a 54-kDa protein.
Thyroid hormone binding ratio (THBR) is a thyroid function test that measures the "uptake" of T3 or T4 tracer by thyroid-binding globulin (TBG) in a given serum sample. This provides an indirect and reciprocal estimate of the available binding sites on TBG within the sample. The results are then reported as a ratio to normal serum.
Blood Urea Nitrogen (BUN) 8-23 × 10 −5: Bradykinin: 7 × 10 −11: Bromide: 7-10 × 10 −9: Cadmium: normal 1-5 × 10 −9: toxic 0.1-3 × 10 −6: Calciferol (vitamin D 2) Maintain calcium and phosphorus levels 1.7-4.1 × 10 −8: Calcitonin (CT) Hormone <1.0 × 10 −10: Calcium: Bones, Ca 2+ ionized 4.48-4.92 × 10 −5: 4.25-5.25 × 10 ...
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In other words, a rise in thyroglobulin levels in the blood may be a sign that thyroid cancer cells are growing and/or the cancer is spreading. [11] Hence, thyroglobulin levels in the blood are mainly used as a tumor marker [ 13 ] [ 11 ] for certain kinds of thyroid cancer (particularly papillary or follicular thyroid cancer).
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