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  2. Is Sildenafil Safe for This Common Male Problem? - AOL

    www.aol.com/sildenafil-safe-common-male-problem...

    Sildenafil is most commonly prescribed to be taken one time per day in doses between 25 and 100 mg for ED. Your healthcare provider will determine the best dosage for you based on a number of factors.

  3. Viagra: What It Treats & Its Side Effects ( Plus What It Was ...

    www.aol.com/viagra-treats-side-effects-plus...

    A single tablet of sildenafil can do that — typically, one dose is all that’s required to produce a firmer, longer-lasting hardness. Studies have shown a 70 to 80 percent success rate in ...

  4. Your ED Pill Guide: Everything You Need to Know Before ... - AOL

    www.aol.com/ed-pill-guide-everything-know...

    Viagra (or sildenafil) lasts three to five hours after it’s consumed. Cialis (tadalafil) has a half-life of 17.5 hours, meaning this drug lasts up to 36 hours after it’s consumed.

  5. Sildenafil - Wikipedia

    en.wikipedia.org/wiki/Sildenafil

    Sildenafil's brand name, Viagra, is widely recognized in popular culture, and the drug's association with treating erectile dysfunction has led to its recreational use. [33] The reasons behind such use include the belief that the drug increases libido, improves sexual performance, [ 33 ] or permanently increases penis size. [ 34 ]

  6. Erectile dysfunction - Wikipedia

    en.wikipedia.org/wiki/Erectile_dysfunction

    The current most common treatment for ED, the oral PDE5 inhibitor known as sildenafil (Viagra) was approved for use for Pfizer by the FDA in 1998, which at the time of release was the fastest selling drug in history.

  7. PDE5 inhibitor - Wikipedia

    en.wikipedia.org/wiki/PDE5_inhibitor

    Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.

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