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The peroxisome of plant cells is polarised when fighting fungal penetration. Infection causes a glucosinolate molecule to play an antifungal role to be made and delivered to the outside of the cell through the action of the peroxisomal proteins (PEN2 and PEN3). [22] Peroxisomes in mammals and humans also contribute to anti-viral defense.
A peroxisome is a type of microbody that functions to help the body break down large molecules and detoxify hazardous substances. It contains enzymes like oxidase, react hydrogen peroxide as a byproduct of its enzymatic reactions. Within the peroxisome, hydrogen peroxide can then be converted to water by enzymes like catalase and peroxidase.
All peroxisomal proteins are synthesized in the cytoplasm and must be directed to the peroxisome. [2] The first step in this process is the binding of the protein to a receptor. The receptor then directs the complex to the peroxisome. Receptors recognize and bind to a region of the peroxisomal protein called a peroxisomal targeting signal, or PTS.
103737 Ensembl ENSG00000108733 ENSMUSG00000018733 UniProt O00623 Q8VC48 RefSeq (mRNA) NM_000286 NM_134025 NM_001364762 NM_001364763 RefSeq (protein) NP_000277 NP_598786 NP_001351691 NP_001351692 Location (UCSC) Chr 17: 35.57 – 35.58 Mb Chr 11: 83.19 – 83.19 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Peroxisome assembly protein 12 is a protein that in humans is encoded by the ...
The peroxisome is an organelle in the cell similar to the lysosome that functions to detoxify the cell. Peroxisomes contain many different enzymes, such as catalase, and their main function is to neutralize free radicals and detoxify drugs. For this reason peroxisomes are ubiquitous in the liver and kidney.
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Peroxisome biogenesis factor 1, also known as PEX1, is a protein which in humans is encoded by the PEX1 gene. [ 5 ] This gene encodes a member of the AAA protein family, a large group of ATPases associated with diverse cellular activities.
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