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Pilocarpine, sold under the brand name Pilopine HS among others, is a lactone alkaloid originally extracted from plants of the Pilocarpus genus. [4] It is used as a medication to reduce pressure inside the eye and treat dry mouth.
Light entering the eye strikes three different photoreceptors in the retina: the familiar rods and cones used in image forming and the more newly discovered photosensitive ganglion cells. The ganglion cells give information about ambient light levels, and react sluggishly compared to the rods and cones.
Prostaglandin analogs such as latanoprost or bimatoprost, beta-blockers such as timolol, alpha-2 agonists such as brimonidine, muscarinic agents such as pilocarpine, hyperosmotic agents such as mannitol and carbonic anhydrase inhibitors such as acetazolamide, methazolamide or dorzolamide are the drugs used to decrease IOP. [5] [6]
The usual treatment of a standardised Adie syndrome is to prescribe reading glasses to correct for impairment of the eye(s). [1] Pilocarpine drops may be administered as a treatment as well as a diagnostic measure. [1] Thoracic sympathectomy is the definitive treatment of diaphoresis, if the condition is not treatable by drug therapy. [1]
The spur is an annular structure composed of collagen in the human eye. It is the origin of the longitudinal and circular fibres (which swerve acutely from the spur to run circumferentially, as a sphincter near the periphery of the lens ) [ 1 ] of the ciliary muscle , and is attached posteriorly to the trabecular meshwork .
Eye accommodation. miosis when M3 is stimulated or mydriasis otherwise. Iris sphincter muscle; cerebral vascular vasodilation and/or systemic vascular vasodilation depending on the location of M3. [14] [13] induce emesis; no: no: G q: acetylcholine [5] arecoline [22] bethanechol; carbachol [5] [12] oxotremorine [12] pilocarpine (in eye ...
One well-known imidazole alkaloid is pilocarpine, which is present in the leaves of Paraguay jaborandi. For instance, from the seeds of garden cress ...
Pilocarpine is a drug that acts as a muscarinic receptor agonist that is used to treat glaucoma Cevimeline (AF102B) (Evoxac®) is a muscarinic agonist that is a Food and Drug Administration (FDA)- approved drug and used for the management of dry mouth in Sjögren's syndrome
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