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Congenital red–green color blindness affects a large number of individuals, especially individuals of European ancestry, where 8% of men and 0.4% of women exhibit congenital red–green color deficiency. [19] The lower prevalence in females is related to the x-linked inheritance of
An issue with color selection is that the colors with the greatest contrast to the red–green color blind tend to be colors of confusion to the blue–yellow color blind and vice versa. In 2018, UX designer Allie Ofisher published 3 color palettes with 6 colors each, distinguishable for all variants of color blindness.
The most common X-linked recessive disorders are: [7] Red–green color blindness, also known as daltonism, [8] which affects roughly 7% to 10% of men and 0.49% to 1% of women. Its relative benignity may explain its commonness.
X-linked recessive conditions include the serious diseases hemophilia A, Duchenne muscular dystrophy, and Lesch–Nyhan syndrome, as well as common and less serious conditions such as male pattern baldness and red–green color blindness. X-linked recessive conditions can sometimes manifest in females due to skewed X-inactivation or monosomy X ...
The incidence of X-linked recessive conditions in females is the square of that in males: for example, if 1 in 20 males in a human population are red–green color blind, then 1 in 400 females in the population are expected to be color-blind (1 / 20)*(1 / 20). Examples include: Aarskog–Scott syndrome; Adrenoleukodystrophy (ALD)
Blue cone monochromacy (BCM) is an inherited eye disease that causes severe color blindness, poor visual acuity, nystagmus, hemeralopia, and photophobia due to the absence of functional red (L) and green (M) cone photoreceptor cells in the retina. BCM is a recessive X-linked disease and almost exclusively affects XY karyotypes.
Haemophilia and red-green colour blindness are recessive, X-linked, pseudodominant genetic disorders, expressed mainly in human males because human females need to be homozygous (i.e., to have inherited the recessive allele from both parents) to show these traits. [citation needed]
Females, instead, require both X chromosomes to have the illness, and as a result could potentially only be a carrier of genetic illness, since their second X chromosome overrides the first. For example, hemophilia A and B and congenital red–green color blindness run in families this way.
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