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EPOCH is an intensive chemotherapy regimen intended for treatment of aggressive non-Hodgkin's lymphoma. [1] [2] It is often combined with rituximab. In this case it is called R-EPOCH or EPOCH-R. The R-EPOCH regimen consists of: Rituximab: an anti-CD20 monoclonal antibody, which has the ability to kill B cells, be they normal or malignant;
Although it has been 50 years from the discovery of anthracyclines, and despite recent advances in the development of targeted therapies for cancers, around 32% of breast cancer patients, 57%-70% of elderly lymphoma patients and 50–60% of childhood cancer patients are treated with anthracyclines. [4]
Of the many forms of lymphoma, some are categorized as indolent (e.g. small lymphocytic lymphoma), compatible with a long life even without treatment, whereas other forms are aggressive (e.g. Burkitt's lymphoma), causing rapid deterioration and death. However, most of the aggressive lymphomas respond well to treatment and are curable.
Cancer treatment has progressed to combine different methods to improve the chances of survival. Surgery and radiation therapy are used to control cancer in specific areas, while systemic therapies (such as chemotherapy , endocrine therapy , targeted therapies , and bisphosphonates ) are used to manage widespread cancer or cancer that has ...
Many cancer patients do not respond to immune checkpoint blockade. Response rate may be improved by combining that with additional therapies, including those that stimulate T cell infiltration. For example, targeted therapies such as radiotherapy, vasculature targeting agents, and immunogenic chemotherapy [ 171 ] can improve immune checkpoint ...
I was told I had stage 4B Hodgkin’s lymphoma, a rare form of cancer that can affect people in their 20s and 30s. My response to the diagnosis was numbness—then, I felt immediately bombarded ...
Lymphoma and a variety of autoimmune diseases, although it may be ineffective in treating IgA-mediated diseases. [ 13 ] Cardiac arrest , cytokine release syndrome , tumor lysis syndrome and acute kidney injury , infections, [ 14 ] hepatitis B reactivation, immune toxicity, pulmonary toxicity, [ 15 ] bowel obstruction and perforation [ 16 ] [ 17 ...
Transitional cell carcinoma, a type of cancer most commonly seen in a dog's bladder, may respond to ivermectin in the same way as human renal cell carcinoma. Unfortunately, there is not yet any ...