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An ejection fraction (EF) is the volumetric fraction (or portion of the total) of fluid (usually blood) ejected from a chamber (usually the heart) with each contraction (or heartbeat). It can refer to the cardiac atrium , [ 1 ] ventricle , [ 2 ] gall bladder, [ 3 ] or leg veins, [ 4 ] although if unspecified it usually refers to the left ...
Heart failure is categorized by a measurement known as ejection fraction. Ejection fraction is the amount of blood that the left ventricle of your heart pumps out each time it contracts ...
Increased risk of heart failure (RR = 5.11) and decline in left ventricular ejection fraction (relative risk RR = 1.83) were seen in these trials as well. [39] Two trials involving shorter term treatment with trastuzumab did not differ in efficacy from longer trials, but produced less cardiac toxicity. [39]
The key indication for CRT is left bundle branch block (LBBB) of the heart, a cardiac abnormality leading to delayed left ventricular contraction. LBBB causes a QRS prolongation of ≥120 ms on the electrocardiogram, contributing to poor left ventricular coordination and reduced systolic function, thereby reduced ejection fraction (<35%).
This is defined as a left ventricular ejection fraction (LVEF) of 40% or less. About half of heart failure patients have a reduced ejection fraction. [2] Other types of heart failure are heart failure with mildly reduced ejection fraction (LVEF between 40% and 50%) and heart failure with preserved ejection fraction (LVEF 50% or higher). [1] [3]
The major predictors of mortality are the severity of mitral regurgitation and reduction in ejection fraction. [ 63 ] Close monitoring and treatment, if necessary, is recommended for those with severe MVP to prevent complications and reduce the risk of mortality.
In some cancer types, prolongation of the fraction schedule over too long can allow for the tumor to begin repopulating, and for these tumor types, including head-and-neck and cervical squamous cell cancers, radiation treatment is preferably completed within a certain amount of time.
In 2018, Eko's low ejection fraction screening algorithm, developed with the Mayo Clinic, received a ‘Breakthrough Device’ designation from the FDA. [5] In 2020, Eko announced $65 million in funding, [6] and a collaboration with 3M. [7] Eko raised an additional $30M in funding in 2022, [8] and received FDA clearance for its murmur analysis ...