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Bronchiolitis obliterans when it occurs following a lung transplant is known as bronchiolitis obliterans syndrome (BOS). [11] [4] BOS is defined as a person who has had either a HSCT or lung transplant and develops symptoms or radiographic findings consistent with bronchiolitis obliterans, but has not been confirmed by biopsy. [22] [44]
Cryptogenic organizing pneumonia; Other names: Bronchiolitis obliterans with organizing pneumonia, idiopathic interstitial pneumonia [1]: Micrograph showing a Masson body (off center left/bottom of the image – pale circular and paucicellular), as may be seen in cryptogenic organizing pneumonia.
Typical symptoms are of recurrent respiratory tract infections, but some have no symptoms. [2] As a result of childhood bronchiolitis obliterans, typically following adenovirus infection, there is a reduction in blood vessels and overextended alveoli, resulting in air trapping in one or part of one lung. [1]
[5] [6] Often when people refer to bronchiolitis, they are referring to acute bronchiolitis in children. [5] Acute bronchiolitis is usually the result of viral infection by respiratory syncytial virus (RSV) (59.2% of cases) or human rhinovirus (19.3% of cases). [7] Diagnosis is generally based on symptoms. [1]
The tree-in-bud sign is a nonspecific imaging finding that implies impaction within bronchioles, the smallest airway passages in the lung. The differential for this finding includes malignant and inflammatory etiologies, either infectious or sterile.
An early warning system (EWS), sometimes called a between-the-flags or track-and-trigger chart, is a clinical tool used in healthcare to anticipate patient deterioration by measuring the cumulative variation in observations, most often being patient vital signs and level of consciousness. [1]
Respiratory bronchiolitis is a lung disease associated with tobacco smoking. [1] In pathology, it is defined by the presence of " smoker's macrophages ". [ 1 ] When manifesting significant clinical symptoms it is referred to as respiratory bronchiolitis interstitial lung disease (RB-ILD).
[1] [9] Diagnosis is typically based on a person's signs and symptom. [4] The color of the sputum does not indicate if the infection is viral or bacterial. [1] Determining the underlying organism is typically not needed. [1] Other causes of similar symptoms include asthma, pneumonia, bronchiolitis, bronchiectasis, and COPD.