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This story was reviewed by Mike Bohl, MD. In the ‘80s, researchers set out to test a medication called sildenafil citrate for treating high blood pressure and angina (chest pain) from heart disease.
Supplements widely marketed to men for performance, energy and sex drive are testing positive for prescription drugs that could have dangerous side effects. Your performance supplement may contain ...
Most men and women know at least vaguely what Viagra does, but not everyone knows how it does it. ... (and brand-name Viagra) is a medication for the treatment of ED, Raynaud’s phenomenon, and ...
Sildenafil's brand name, Viagra, is widely recognized in popular culture, and the drug's association with treating erectile dysfunction has led to its recreational use. [33] The reasons behind such use include the belief that the drug increases libido, improves sexual performance, [ 33 ] or permanently increases penis size. [ 34 ]
When you have more than one health condition, things start to get complicated. Life-threatening problems can result when drug interactions between your daily medications cause side effects, and ...
Sildenafil did not prove effective for coronary heart disease but an interesting side effect was discovered, a penile erection. That side effect soon became the main field of investigation. [23] The inhibitor is highly selective for the PDE5 family. [22] Sildenafil is a prototype of PDE5 inhibitors that Pfizer launched as Viagra.
Whether you’re one of the 30 million men who have (ED) or not, you’ve almost certainly heard of Viagra. Maybe you even know about other ED medications, like Levitra or Stendra or Cialis, too.
Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.
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