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Chemotherapy targets cells that grow rapidly, such as tumors, but can also affect white blood cells, because they are characterized by bone marrow as rapid growing. [5] A common side effect of cancer treatment is neutropenia , the lowering of neutrophils (a specific type of white blood cell).
Cancer Cell is internationally regarded as one of the top cancer research and oncology journals. According to the Journal Citation Reports, the 2022 impact factor of the journal is 50.3. It is part of the Cell Press portfolio, which is owned by Elsevier. Issues are published monthly in print and online versions.
Tumor stroma and extracellular matrix in hypoxia. Tumor hypoxia is the situation where tumor cells have been deprived of oxygen.As a tumor grows, it rapidly outgrows its blood supply, leaving portions of the tumor with regions where the oxygen concentration is significantly lower than in healthy tissues.
Blood cell counts: Deviations in specific blood cells can point to an immune system anomaly. Immune system cells: These assessments are used to measure the levels of various immune cells. Genetic testing involves collecting samples from patients for molecular analysis when there is a suspicion of inborn errors in immunity.
The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as indexed by Clarivate's Web of Science.
Cancer Discovery has become a premier journal in the field of cancer research, with a 2020 impact factor of 39.397 that is the highest among the AACR journals. [6] [7] Research published in the journal includes identification of actionable genomic alterations in cancer, mechanisms of therapy resistance, clinical trials on targeted therapy, and ...
It covers research on all aspects of cancer and cancer-related biomedical sciences and was established in 1941. The editor-in-chief is Chi Van Dang. [1] The journal was established in 1916 as the Journal of Cancer Research, was renamed American Journal of Cancer in 1931, and obtained its current name in 1941.
DBA causes low red blood cell counts , without substantially affecting the other blood components (the platelets and the white blood cells), which are usually normal. This is in contrast to Shwachman–Bodian–Diamond syndrome , in which the bone marrow defect results primarily in neutropenia , and Fanconi anemia , where all cell lines are ...