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The LD 50 of nicotine is 50 mg/kg for rats and 3 mg/kg for mice. 0.5–1.0 mg/kg can be a lethal dosage for adult humans, and 0.1 mg/kg for children. [19] [20] However the widely used human LD 50 estimate of 0.5–1.0 mg/kg was questioned in a 2013 review, in light of several documented cases of humans surviving much higher doses; the 2013 review suggests that the lower limit causing fatal ...
It may be drunk accidentally or intentionally in a suicide attempt. [2] When broken down by the body it results in glycolic acid and oxalic acid which cause most of the toxicity. [1] [4] The diagnosis may be suspected when calcium oxalate crystals are seen in the urine or when acidosis or an increased osmol gap is present in the blood. [1]
Conditions which disrupt coordination of swallowing above the glottis put a patient at increased risk for aspiration. This is referred to as oropharyngeal dysphagia and can be a result of structural abnormalities ( strictures , stenosis, mediastinal and neck masses, etc.), connective tissue diseases, neuropathy, or other central nervous system ...
A former inmate convicted of smuggling illegal drugs into Bucks County jail that resulted in the overdose death of a prisoner is alleging that he nearly died last year after corrections employees ...
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Nicotine is a water soluble chemical, therefore the risk of GTS is elevated if this chemical from the tobacco plants mixes with any sort of moisture. [ 2 ] [ 3 ] Green Tobacco Sickness is characterized by a wide range of symptoms, including nausea , vomiting , headache , dizziness , and severe weakness. [ 4 ]
A Taiwanese man who accidentally swallowed an Apple Airpod while sleeping was surprised to find out it still worked after it passed through his system, the Daily Mail reports.. Ben Hsu, a navy ...
Cotinine has an in vivo half-life of approximately 20 hours, and is typically detectable for several days (up to one week) after the use of tobacco. The level of cotinine in the blood, saliva, and urine is proportionate to the amount of exposure to tobacco smoke, so it is a valuable indicator of tobacco smoke exposure, including secondary (passive) smoke. [14]