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  2. Neurobiological effects of physical exercise - Wikipedia

    en.wikipedia.org/wiki/Neurobiological_effects_of...

    Neuroplasticity is the process by which neurons adapt to a disturbance over time, and most often occurs in response to repeated exposure to stimuli. [27] Aerobic exercise increases the production of neurotrophic factors [note 1] (e.g., BDNF, IGF-1, VEGF) which mediate improvements in cognitive functions and various forms of memory by promoting blood vessel formation in the brain, adult ...

  3. Brain-derived neurotrophic factor - Wikipedia

    en.wikipedia.org/wiki/Brain-derived_neurotrophic...

    Brain-derived neurotrophic factor (BDNF), or abrineurin, [5] is a protein [6] that, in humans, is encoded by the BDNF gene. [7] [8] BDNF is a member of the neurotrophin family of growth factors, which are related to the canonical nerve growth factor (NGF), a family which also includes NT-3 and NT-4/NT-5.

  4. Tropomyosin receptor kinase B - Wikipedia

    en.wikipedia.org/wiki/Tropomyosin_receptor_kinase_B

    In addition, combining the induction of adult hippocampal neurogenesis and increasing BDNF levels lead to an improved cognition, mimicking exercise benefits in AD mouse models. [23] The effect of TrkB/BDNF signalling on AD pathology has been shown to be in part mediated by an increase in δ-secretase levels, via an upregulation of the JAK2 ...

  5. Interleukin 6 - Wikipedia

    en.wikipedia.org/wiki/Interleukin_6

    3569 16193 Ensembl ENSG00000136244 ENSMUSG00000025746 UniProt P05231 P08505 RefSeq (mRNA) NM_000600 NM_001318095 NM_001371096 NM_031168 NM_001314054 RefSeq (protein) NP_000591 NP_001305024 NP_001358025 NP_001300983 NP_112445 Location (UCSC) Chr 7: 22.73 – 22.73 Mb Chr 5: 30.22 – 30.22 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Interleukin 6 (IL-6) is an interleukin that acts ...

  6. Cerebrolysin - Wikipedia

    en.wikipedia.org/wiki/Cerebrolysin

    Cerebrolysin (developmental code name FPF-1070) is an experimental mixture of enzymatically-treated peptides derived from pig brain whose constituents can include brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF), nerve growth factor (NGF), and ciliary neurotrophic factor (CNTF).

  7. rs6265 - Wikipedia

    en.wikipedia.org/wiki/Rs6265

    A number of studies have examined the role of this polymorphism in risk of neuropsychiatric disorders [1], including schizophrenia [2] and depression. [3] It is generally thought that some variants of the polymorphism lead to memory impairment and susceptibility to neuropsychiatric disorders, [4] and a 2007 meta-analysis of case-control studies found a relationship between the SNP and ...

  8. Neurotrophic hypothesis of depression - Wikipedia

    en.wikipedia.org/wiki/Neurotrophic_hypothesis_of...

    The neurotrophic hypothesis of depression [1] proposes that major depressive disorder (MDD) is caused, at least partly, by impaired neurotrophic support.Neurotrophic factors (also known as neurotrophins) are a family of closely related proteins which regulate the survival, development, and function of neurons in both the central and peripheral nervous systems.

  9. Neuroplasticity - Wikipedia

    en.wikipedia.org/wiki/Neuroplasticity

    Neuroplasticity, also known as neural plasticity or just plasticity, is the ability of neural networks in the brain to change through growth and reorganization. . Neuroplasticity refers to the brain's ability to reorganize and rewire its neural connections, enabling it to adapt and function in ways that differ from

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