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Experts explain proven and new rescue therapies and migraine prevention protocols as well as which patients should and shouldn't try them.
Rescue treatment involves acute symptomatic control with medication. [4] Recommendations for rescue therapy of migraine include: (1) migraine-specific agents such as triptans, CGRP antagonists, or ditans for patients with severe headaches or for headaches that respond poorly to analgesics, (2) non-oral (typically nasal or injection) route of administration for patients with vomiting, (3) avoid ...
Dihydroergotamine (DHE), sold under the brand names D.H.E. 45 and Migranal among others, is an ergot alkaloid used to treat migraines. [7] It is a derivative of ergotamine. It is administered as a nasal spray or injection and has an efficacy similar to that of sumatriptan. Nausea is a common side effect. [8]
CGRP antagonists can be used for both acute migraine treatment as well as prophylactically. [14] CGRP is a neuropeptide which is thought to induce migraines via vasodilation of cranial arteries. [14] CGRP can also release inflammatory agents and cause nervous system sensitization. [14]
Migraine is a brain disorder that causes your neurons (i.e., the nerves in your brain) to become “hyperactive,” explains Cynthia Armand, MD, a migraine specialist for the Montefiore Health ...
Memantine, which is used in the treatment of Alzheimer's Disease, is beginning to be used off label for the treatment of migraine. It has not yet been approved by the FDA for the treatment of migraine. Aspirin can be taken daily in low doses such as 80 mg. The blood thinners in ASA have been shown to help some migraineurs, especially those who ...
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