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At the end, the end of a signal pathway leads to the regulation of a cellular activity. This response can take place in the nucleus or in the cytoplasm of the cell. A majority of signaling pathways control protein synthesis by turning certain genes on and off in the nucleus. [45]
In smaller cells, the diffusion of molecules is more rapid, but diffusion slows as the size of the cell increases, so larger cells may need cytoplasmic streaming for efficient function. [1] The green alga genus Chara possesses some very large cells, up to 10 cm in length, [2] and cytoplasmic streaming has been studied in these large cells. [3]
As the complex reaches the NPC, it diffuses through the pore without the need for additional energy. Upon entry into nucleus, RanGTP binds to Importin-β and displaces it from the complex. Then the cellular apoptosis susceptibility protein (CAS), an exportin which in the nucleus is bound to RanGTP, displaces Importin-α from the cargo. The NLS ...
Nucleoplasm is quite similar to the cytoplasm, with the main difference being that nucleoplasm is found inside the nucleus while the cytoplasm is located inside the cell, outside of the nucleus. Their ionic compositions are nearly identical due to the ion pumps and permeability of the nuclear envelope, however, the proteins in these two fluids ...
The small size of actin (about 43 kDa) allows it to enter the nucleus by passive diffusion. [21] The import of actin into the nucleus (probably in a complex with cofilin) is facilitated by the import protein importin 9. [22] Low levels of actin in the nucleus seems to be important, because actin has two nuclear export signals (NES) in its sequence.
The nuclear envelope, also known as the nuclear membrane, [1] [a] is made up of two lipid bilayer membranes that in eukaryotic cells surround the nucleus, which encloses the genetic material. The nuclear envelope consists of two lipid bilayer membranes: an inner nuclear membrane and an outer nuclear membrane. [4]
Cell fusion is an important cellular process in which several uninucleate cells (cells with a single nucleus) combine to form a multinucleate cell, known as a syncytium.Cell fusion occurs during differentiation of myoblasts, osteoclasts and trophoblasts, during embryogenesis, and morphogenesis. [1]
The cytoplasm describes all the material within a eukaryotic or prokaryotic cell, enclosed by the cell membrane, including the organelles [1] and excluding the nucleus in eukaryotic cells. The material inside the nucleus of a eukaryotic cell and contained within the nuclear membrane is termed the nucleoplasm.