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Cathepsin E is an enzyme (EC 3.4.23.34) that in humans is encoded by the CTSE gene. [5] [6] [7] The enzyme is also known as slow-moving proteinase, erythrocyte membrane aspartic proteinase, SMP, EMAP, non-pepsin proteinase, cathepsin D-like acid proteinase, cathepsin E-like acid proteinase, cathepsin D-type proteinase) is an enzyme.
162,041 structures in the PDB have a structure factor file. 11,242 structures have an NMR restraint file. 5,774 structures in the PDB have a chemical shifts file. 13,388 structures in the PDB have a 3DEM map file deposited in EM Data Bank. Most structures are determined by X-ray diffraction, but about 7% of structures are determined by protein ...
The Ii is then cleaved by cathepsin S (cathepsin L in cortical thymic epithelial cells), leaving only a small fragment called CLIP remaining bound to the groove of MHC class II molecules. The rest of the Ii is degraded. [10] CLIP blocks peptide-binding until HLA-DM interacts with MHC II, releasing CLIP and allowing other peptides to bind. In ...
Initial efforts to purify and characterize proteases using hemoglobin transpired at a time when the word "cathepsin" indicated a single enzyme; [28] the existence of multiple, distinct cathepsin family members (e.g. B, H, L) did not appear to be understood at the time. However, by 1937 Bergmann and colleagues began to differentiate cathepsins ...
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We asked dietitians to rank 10 popular canned tunas and this was the winner. News. News. USA TODAY. Israel set to approve Gaza ceasefire, hostage deal, Netanyahu's office says. News. NY Post.
22223 Ensembl ENSG00000154277 ENSMUSG00000029223 UniProt P09936 Q9R0P9 RefSeq (mRNA) NM_004181 NM_011670 RefSeq (protein) NP_004172 NP_035800 Location (UCSC) Chr 4: 41.26 – 41.27 Mb Chr 5: 66.83 – 66.84 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Ubiquitin carboxy-terminal hydrolase L1 (EC 3.1.2.15, ubiquitin C-terminal hydrolase, UCH-L1) is a deubiquitinating enzyme ...
On the premiere episode of her new podcast, Khloé Kardashian recalled her "crazy, drunk" wrestling match with Scott Disick during Kim Kardashian and Kanye West's 2014 rehearsal dinner