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Vitamin C supplements among other dietary supplements at a US drug store. Vitamin C has a definitive role in treating scurvy, which is a disease caused by vitamin C deficiency. Beyond that, a role for vitamin C as prevention or treatment for various diseases is disputed, with reviews often reporting conflicting results.
In the early 2010s, in vitro preclinical and clinical trials were undertaken to investigate the pharmacological mechanism of action of intravenous ascorbic acid therapy. [ 35 ] [ 36 ] These findings demonstrated ascorbic acid's pro-oxidant capabilities to produce hydrogen peroxide and thus, proposed a possible pharmacological mechanism of ...
The literature contains many reports on the antiviral effects of vitamin C, [14] and one study suggests dehydroascorbic acid has stronger antiviral effects and a different mechanism of action than ascorbic acid. [15]
C 6 H 6 O 6 • − + L• + H 2 O + H + → C 6 H 8 O 7 + LH 2 C 6 H 6 O 6 • − + H 2 O + H + → C 6 H 8 O 7 + C 6 H 7 O − 6. Aqueous solutions of dehydroascorbate are unstable, undergoing hydrolysis with a half-life of 5–15 minutes at 37 °C (99 °F). Decomposition products include diketogulonic acid, xylonic acid, threonic acid and ...
The relative importance of the antioxidant and pro-oxidant activities of antioxidants is an area of current research, but vitamin C, which exerts its effects as a vitamin by oxidizing polypeptides, appears to have a mostly antioxidant action in the human body. [94]
Protein C, also known as autoprothrombin IIA and blood coagulation factor XIV, [5]: 6822 [6] is a zymogen, that is, an inactive enzyme.The activated form plays an important role in regulating anticoagulation, inflammation, and cell death and maintaining the permeability of blood vessel walls in humans and other animals.
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