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The muscle biopsy will demonstrate the nemaline rods, but as they are less than 1 μm in length they are easily overlooked. The sections must be trichromatically stained and sectioned at a thickness of 2 to 4 μm for effective visualization. Immunostains for myotilin and α-actinin all but clinch the diagnosis.
As the calcifications will typically resolve after a period of time, non-surgical treatment is encouraged to minimize the unpleasant symptoms and maximize the function of the affected limb. [ 5 ] Following a skeletal muscle injury, the affected limb should be immobilized with bed rest, ice therapy, compression, and elevation of the affected limb.
A diagnosis of functional PAES is made if symptoms are improved after Botulinum injection. However, If symptoms are persisted, the patient can undergo an additional Botulinum injection or proceed with surgical decompression. [27] The outcome following the surgery is usually favorable. Successful resolution of PAES occurs in 77 percent of cases ...
Prodromal symptoms are typically fever, cough, and rhinorrhea. BACM symptoms that follow are most frequently calf pain, gait complaints, and inability to walk. [2] The condition is self-limited and full restitution can be expected. In very rare cases, however, rhabdomyolysis may develop. [1]
Intermittent claudication, also known as vascular claudication, is a symptom that describes muscle pain on mild exertion (ache, cramp, numbness or sense of fatigue), [1] classically in the calf muscle, which occurs during exercise, such as walking, and is relieved by a short period of rest.
Often there are no symptoms. [2] If symptoms do occur these may include swelling and pain behind the knee, or knee stiffness. [1] If the cyst breaks open, pain may significantly increase with swelling of the calf. [1] Rarely complications such as deep vein thrombosis, peripheral neuropathy, ischemia, or compartment syndrome may occur. [2] [3]
Muscle strain is a common cause of calf injury, which can happen from activities like running or jumping without a proper warmup. Overuse like excessive exercise without enough time for recovery ...
Signs and symptoms include exercise intolerance, muscle fatigue, muscle cramps, myalgia, delayed muscle relaxation (pseudomyotonia), proximal muscle weakness, delayed deep tendon reflexes (hyporeflexia) especially of the ankles, and a pseudoathletic appearance of hypertrophic calf muscles.