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  2. p16 - Wikipedia

    en.wikipedia.org/wiki/P16

    p16 (also known as p16 INK4a, cyclin-dependent kinase inhibitor 2A, CDKN2A, multiple tumor suppressor 1 and numerous other synonyms), is a protein that slows cell division by slowing the progression of the cell cycle from the G1 phase to the S phase, thereby acting as a tumor suppressor.

  3. INK4 - Wikipedia

    en.wikipedia.org/wiki/Ink4

    The INK4a/ARF/INK4b Locus. [1] The INK4a/ARF/INK4b locus encodes three genes (p15INK4b, ARF, and p16INK4a) in a 35-kilobase stretch of the human genome. P15INK4b has a different reading frame that is physically separated from p16INK4a and ARF. P16INK4a and ARF have different first exons that are spliced to the same second and third exon.

  4. Rabbit hybridoma - Wikipedia

    en.wikipedia.org/wiki/Rabbit_hybridoma

    The rabbit formed a myeloma-like tumor, allowing the isolation of a plasmacytoma cell line, named 240E-1. Fusion of 240E-1 cells with rabbit lymphocytes produced hybridomas that secreted rabbit monoclonal antibodies in a consistent manner. [4] However, like the early mouse myeloma lines developed in the 1970s, stability was a concern.

  5. Pfizer's bladder cancer therapy meets main goal in late-stage ...

    www.aol.com/news/pfizers-bladder-cancer-therapy...

    The antibody treatment, sasanlimab, in combination with Bacillus Calmette-Guérin (BCG) vaccine met the main goal of the study in patients with high-risk non-muscle invasive bladder cancer (NMIBC ...

  6. CDKN2A - Wikipedia

    en.wikipedia.org/wiki/CDKN2A

    During this process, a feedback loop exists between P16 and Rb, and P16 expression is controlled by Rb. [22] [23] P16/Rb pathway collaborates with the mitogenic signaling cascade for the induction of reactive oxygen species, which activates the protein kinase C delta, leading to an irreversible cell cycle arrest. Thus P16 participates not only ...

  7. ‘Why we never got Ebola’ by Huffington Post

    testkitchen.huffingtonpost.com/ebola

    What one nurse learned about humanity amidst the Ebola epidemic

  8. Russia tells its citizens: avoid travel to the West - AOL

    www.aol.com/news/russia-tells-citizens-avoid...

    MOSCOW (Reuters) -Russia said on Wednesday that relations with Washington were so confrontational that Russian citizens should not visit the United States, Canada and some EU countries in coming ...

  9. 18-Year-Old Charged with Double Murder of Teen Stepsisters ...

    www.aol.com/18-old-charged-double-murder...

    A suspect has been arrested following the reported shooting of Alabama stepsisters Kayden Lynch, 19, and Madison Daly, 18, on Christmas Eve. Per Lee County outlet The Observer, 18-year-old Jalen ...

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